Results 221 to 230 of about 158,042 (243)

Establishment of NE asymmetry — targeting of membrane proteins to the inner nuclear membrane

Current Opinion in Cell Biology, 2015
The inner nuclear membrane (INM) represents a specialized subdomain of the endoplasmic reticulum (ER). The INM houses a unique set of integral membrane proteins that perform key functions in the organization of intranuclear architecture, control of gene expression and coupling of the nucleus to the cytoskeleton.
Rosemarie Ungricht, Ulrike Kutay
openaire   +3 more sources

DNA Synthesis associated with the Inner Membrane of the Nuclear Envelope

Nature New Biology, 1971
IN Escherichia coli1 and Bacillus subtilis2, the most recently synthesized DNA was found to be attached to the cell membrane. When human amnion tissue culture cells were briefly exposed to3H-thymidine, electron microscope autoradio- J graphy of the cells showed that the radioactivity was restricted to the nuclear envelope and the periphery of the ...
N S, Mizuno, C E, Stoops, A A, Sinha
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Inner nuclear membrane proteins: impact on human disease

Chromosoma, 2012
In the past decade, the inner nuclear membrane has become a focus of research on inherited diseases. A heterogeneous group of genetic disorders known as laminopathies have been described that result from mutations in genes encoding nuclear lamins, intermediate filament proteins associated with the inner nuclear membrane.
Iván, Méndez-López, Howard J, Worman
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Novel integral membrane proteins of the inner nuclear membrane

2002
0 TITLE PAGE, TABLE OF CONTENTS 1 INTRODUCTION 8 1.1 Functional organization of the cell nucleus 8 1.2 The nuclear envelope 11 1.2.1 The integral proteins of the inner nuclear membrane 14 1.2.2 The lamina 21 1.3 Questions and approaches 23 2 RESULTS AND DISCUSSION 24 2.1 The nuclear envelope proteome 24 2.1.1 Fractionation of nuclear envelopes and the ...
openaire   +1 more source

An In Vitro Assay to Study Targeting of Membrane Proteins to the Inner Nuclear Membrane

2016
Newly synthesized membrane proteins are inserted into the endoplasmic reticulum (ER) from where they are constantly sorted to various cellular compartments. To analyze and visualize sorting of membrane proteins to the inner nuclear membrane (INM), we developed a trap-release system that uncouples membrane integration into the ER from transport.
Rosemarie Ungricht, Sumit Pawar, Ulrike Kutay   +2 more
openaire   +3 more sources

The Inner Nuclear Membrane

Journal of Membrane Biology, 2000
H J, Worman, J C, Courvalin
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Junctions of polytene chromosomes and the inner nuclear membrane

Experientia, 1980
Polytene chromosomes in salivary gland nuclei from chironomid larvae of defined stages are connected along their entire length, by some 100 chromatin fibers, to the inner nuclear membrane.
openaire   +1 more source

Characterization of VAPA at the inner nuclear membrane: localization, membrane insertion and nuclear interactome

Tail-anchored (TA) proteins are type IV single-pass membrane proteins characterized by a long hydrophobic transmembrane domain (TMD) positioned very close to a notably short C-terminus facing the lumen. Due to their topology, most TA proteins require post-translational membrane insertion mechanisms since their TMD only emerges from the ribosome after ...
Rodríguez González, Inés, Kehlenbach, Ralph, Kehlenbach, Ralph, Georg-August-Universität Göttingen, Kehlenbach, Ralph, Krebber, Heike   +5 more
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Characterization of Inner Nuclear Membrane Proteins

GBM Annual Fall meeting Halle 2002, 2002
Henning Otto, Daniel de Graaf, Philip Denner, Luiza Bengtsson   +3 more
openaire   +1 more source

Towards understanding inner nuclear membrane protein degradation in plants

Journal of Experimental Botany, 2022
Yangnan Gu, Enrico Calvanese, Gu Yangnan   +2 more
exaly