Results 71 to 80 of about 2,483,437 (255)

Measurement of innovation capability in supply chain : an exploratory study

open access: yes, 2016
Purpose: The purpose of this paper is to explore the development of innovation capability construct measures in the context of supply chain and to objectively identify the key dimensions for stimulating focal firms' innovativeness.Design/methodology ...
Iddris, Faisal,
core   +1 more source

A knowledge management framework to grow innovation capability maturity

open access: yesSouth African Journal of Information Management, 2012
Background: Innovation is a key prerequisite for being organisationally competitive. Therefore, it is imperative that enterprises grow and mature their innovation capability.
Denéle Esterhuizen   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

China's Regional Inequality in Innovation Capability, 1995-2004 [PDF]

open access: yes
Relying on a recently developed decomposition framework, this paper explores spatial distribution of innovation capability in China. It is found that at the regional level, China's inequality in innovation capability increased from 1995 to 2004.
Fan, Peilei, Wan, Guanghua
core  

Matrix structure for supporting organisational innovation capability [PDF]

open access: yes, 2013
The importance of an organisation's capability to produce innovations has been noticed to be increasingly important. Previous literature has discussed appropriate organisational structures for innovation activities. The matrix structure is widely seen to
Mäkimattila, Martti   +2 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Measuring Regional Innovative Capability [PDF]

open access: yes
Regional innovation environment has experienced remarkable changes in the recent decades. Innovativeness at regional level is seen as a consequence of networked co-operation in a regional innovation system, which sets demands for new kinds of regional ...
Vesa Harmaakorpi, Tomi Tura
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Firms’ digital capabilities and green collaborative innovation: The role of green relationship learning

open access: yesJournal of Innovation & Knowledge
With the growth of the digital economy and environmental concerns, an increasing number of manufacturing firms are leveraging digitalization to advance their green innovation and sustainable development. Although previous studies have examined the impact
Xuemei Xie, Mengge Wang
doaj   +1 more source

Home - About - Disclaimer - Privacy