Results 91 to 100 of about 735,117 (314)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Cluster Innovation Capability: A Systematic Review
International Journal of Innovation, 2018 Bittencourt, B., Galuk, M., Daniel, V., & Zen, A. (2018). Cluster Innovation Capability: a systematic review. International Journal of Innovation, 7(1), 26-44.
Bittencourt, Bruno Anicet +3 more
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The dynamics of national innovation systems: a panel cointegration analysis of the coevolution between innovative capability and absorptive capacity [PDF]
This paper puts forward the idea that the dynamics of national innovation systems is driven by the coevolution of two main dimensions: innovative capability and absorptive capacity.
Fulvio, Castellacci, Jose Miguel, Natera
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Learning to Innovate in Nigeria's cable and wire manufacturing sub-sector: inferences from a firm-level case study [PDF]
Firm performance is known to be connected to firm-level innovation capability. Innovation capability, in turn, is an output of technological learning. This paper evaluates technological learning among firms in the Cable and Wire manufacturing sub-sector ...
Adeniyi, A, Egbetokun, A, Siyanbola, W
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
E-business Model Innovation and Capability Building [PDF]
e-commerce, business models, capacity ...
Gagnon, Stephane
core
Covariance structure analysis of innovation and ICT use among Japanese innovative SMEs [PDF]
, 2013 One of the common features of innovative SMEs identified from our previous surveys and in-depth interviews is innovation capability accumulated inside the firm, which enables them to create new products which meet customer needs and to cooperate with the
Bunno, Teruyuki +2 more
core
Enhancing innovative capability and sustainability of Saudi firms [PDF]
, 2016 © 2016 by the author. The Saudi Arabian government has recognised the need for an alternative path to national development in the form of a knowledge-based economy (KBE). One of the key drivers of a knowledge-based economy KBE is innovation.
Fahad, FA, Sohaib, O
core +1 more source