Results 181 to 190 of about 273,156 (307)

Innovation Hub Technical Specifications

The deliverable describes the building blocks of the ...
openaire   +1 more source

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Mitochondrial Hub Genes in Rheumatoid Arthritis Identified by Machine Learning and Mendelian Randomization with Experimental Validation. [PDF]

J Inflamm Res
Luo X, Dong Z, Song Y, Hu J, Liao S, Ding X.   +5 more
europepmc   +1 more source

Innovation Hub: First Release

The first version of the platform is released after the needs gathering stage (T4.3).
openaire   +1 more source

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

Advanced Science, EarlyView.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song, Jingyang Liu, Xue Wang, Minpu Zhang, Changgang Sun   +4 more
wiley   +1 more source

Charting Africa's digital public health future: Five priorities for action. [PDF]

J Public Health Afr
Ngongo N, Dereje N, Hall S, Kaseya J.
europepmc   +1 more source

Innovation Hub: Second Release

The second version is released after the evaluation stage (T4.5).
openaire   +1 more source

Molecularly Engineered Phenoxazinone‐Skeleton Cascade‐Activated NIR Probes for Monitoring Fe2+/Viscosity in Ferroptosis‐Mediated Parkinson's Disease

Advanced Science, EarlyView.
A series of Fe2+/viscosity cascade‐activated NIR fluorescence probes (NP1–5) are synthesized, and NP3 is selected for its optimal properties. To verify application of NP3 in ferroptosis intervention in PD, PQR NPs, is constructed by NP3 and quercetin self‐assembling.
Lixia Guo, Tao Liu, Hongfei Wang, Qi Gao, Zhaobo Yang, Zumeng Wang, Chenlong Li, Yubing Kang, Kahleong Lim, Wen Liu, Li Lu, Chengwu Zhang   +11 more
wiley   +1 more source

Advanced Synthesis and Unique Properties of 2D Transition Metal Dichalcogenides for Realizing Next-Generation Applications

ACS Materials Au
Chandan Patra, Subrata Mondal, Rupam Mukherjee, Yerumbu Nandakishora   +3 more
doaj   +1 more source

Application of a Conceptual Model for Translational Science Impact. [PDF]

J Clin Transl Sci
Presley JH, Worrell S, Jauregui-Dusseau A, Madden CA, James LP.   +4 more
europepmc   +1 more source