Results 61 to 70 of about 2,390,056 (355)
Administrative SciencesAs governments pursue digital transformation to improve service delivery and administrative efficiency, AI chatbots have emerged as a promising innovation in smart public administration.
Mansur Samadovich Omonov, Yonghan Ahn
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Measuring the Capacity of Organizations Innovation ‒ Major Process of Innovation Management
Amfiteatru Economic, 2015 The article approaches the problem of companies’ success in today’s economic context, characterized by a generalized market with increasing competitive and client requirements.
Dorin Maier +3 more
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
THE NEXUS BETWEEN KNOWLEDGE MANAGEMENT AND INNOVATION. A LITERATURE REVIEW [PDF]
, 2016 Knowledge management is the new managerial discipline whose aim is to support the processes of knowledge exploitation, memorization, re-use and learning.
Bolisani, Ettore, Leon, R. D.
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Customer Engagement and Customer Relationship Management Capabilities’ Effects on Innovation Performance and Customer Distrust’s Moderating Role [PDF]
, 2023 Rima H. Binsaeed +5 more
openalex +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Manageability of Technical Innovation through Technical Property Rights [PDF]
International Journal of Management, Knowledge and Learning, 2016 The term innovation is used in many respects and has been evolving over the last decades. This paper mainly focusses on managing technical innovation and differentiates this kind of innovation from others.
Michael Horeth
doaj
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source