Results 61 to 70 of about 9,827,909 (347)

Evaluation of the economic impact of the iNet [PDF]

open access: yes, 2011
An evaluation of the economic impacts of the iNets (innovation networks) commissioned to assist in the delivery of the East Midlands Regional Innovation Strategy (RIS)
GHK, Smith, R
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Social Innovation by Tourism Strategy in the Western Amazon [PDF]

open access: yes, 2018
This work concerns the strategies of social innovation focused on the concept of inbound tourism and hospitality in Rondônia State, Brazil. The general objective is to study the main strategies for qualifying as a tourist attraction.
Arenhardt, V. (Valeria)   +4 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

A Holistic Approach to Incubator Strategies in the Entrepreneurial Support Ecosystem

open access: yesM@n@gement, 2020
This research employs ecosystem and strategic fit theories to understand incubators’ relationships with other ecosystem actors by investigating the elaboration of specialization, diversification, and co-opetition strategies.
Christina Theodoraki
doaj   +1 more source

Rebiasing: Managing automatic biases over time

open access: yesFrontiers in Psychology, 2022
Automatic preferences can influence a decision maker’s choice before any relevant or meaningful information is available. We account for this element of human cognition in a computational model of problem solving that involves active trial and error and ...
Aleksey Korniychuk, Eric Luis Uhlmann
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A Brief Review of the Four-decade Evolution of Science Popularization in China

open access: yesCultures of Science, 2019
This article presents a brief review of the history, main achievements and challenges faced during the 40-year evolution of science popularization (SP) in China that began with the reform and opening up process.
Fujun Ren PhD
doaj   +1 more source

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