Results 61 to 70 of about 9,827,909 (347)
Evaluation of the economic impact of the iNet [PDF]
An evaluation of the economic impacts of the iNets (innovation networks) commissioned to assist in the delivery of the East Midlands Regional Innovation Strategy (RIS)
GHK, Smith, R
core
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Social Innovation by Tourism Strategy in the Western Amazon [PDF]
This work concerns the strategies of social innovation focused on the concept of inbound tourism and hospitality in Rondônia State, Brazil. The general objective is to study the main strategies for qualifying as a tourist attraction.
Arenhardt, V. (Valeria) +4 more
core +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
A Holistic Approach to Incubator Strategies in the Entrepreneurial Support Ecosystem
This research employs ecosystem and strategic fit theories to understand incubators’ relationships with other ecosystem actors by investigating the elaboration of specialization, diversification, and co-opetition strategies.
Christina Theodoraki
doaj +1 more source
Rebiasing: Managing automatic biases over time
Automatic preferences can influence a decision maker’s choice before any relevant or meaningful information is available. We account for this element of human cognition in a computational model of problem solving that involves active trial and error and ...
Aleksey Korniychuk, Eric Luis Uhlmann
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A Brief Review of the Four-decade Evolution of Science Popularization in China
This article presents a brief review of the history, main achievements and challenges faced during the 40-year evolution of science popularization (SP) in China that began with the reform and opening up process.
Fujun Ren PhD
doaj +1 more source

