Results 111 to 120 of about 1,855,001 (308)
Hybrid Estimation of Inflow Multiphase Production Rates Using a Dynamic Wellbore Flow Model
This paper considers the problem of estimating the quantitative parameters of a two-phase fluid flow in a well based on the dynamic physical flow model.
Anton Gryzlov +3 more
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
When Smoke Enters the City: Challenges for HVAC Filters in Resilient Buildings
Climate-driven increases in wildfire activity threaten urban air quality both through long-range smoke transport from rural fires and direct exposure as the wildland–urban interface expands.
Tanya Shirman, Hediyeh Zamani, Sissi Liu
doaj +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Sex-related differences in fine motor skills and muscle strength control during short-term fasting
Despite the growing relevance of fasting-related effects on health promotion, studies related to its impact on motor behavior remain scarce. Thus, the aims of the present study were to determine the effects of short-term fasting on fine motor skills and ...
Rima Solianik +3 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
ENTREPRENEURS CONFIDENCE IN INNOVATION AND THEIR INNOVATIVENESS
This article tests the hypothesis that entrepreneurs confidence in innovation has a positive effect on their innovativeness. The sample is 550 owner managers sampled from the population of owner managers in Iran in 2010, surveyed in the Global Entrepreneurship Monitor, GEM.
Nochian, Nastooh, Schøtt, Thomas
openaire +4 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Outlaw Community Innovations [PDF]
Recent studies of outlaw communities provide qualitative evidence of their existence and the organisation of the underlying innovation processes. We provide descriptive results from a large scale survey of two online outlaw communities focussing on ...
Schulz, Celine, Wagner, Stefan
core
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source

