Adoption of innovations in harvesting methods of the grape: A case study in Charikar and Bagram districts of Parwan province, Afghanistan [PDF]
, 2020 The main objectives of this study were to determine the extent of innovation in the grape harvest, and the rate of familiarity and usability of innovations by farmers in Parwan province.
Dadkhwah, Zafaruddin
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Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Eurolanguages-2011: Innovations and Development [PDF]
, 2011 Збірник наукових студентських робіт призначено для широкого кола читачів, які цікавляться проблемами вивчення іноземних мов та перекладу в ...
Аллахвердян, Тамара Миколаївна +10 more
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A socio-technical analytical framework on the EHR-organizational innovation interplay: Insights from a public hospital in Greece [PDF]
, 2015 The healthcare sector globally is confronted with increasing internal and external pressures that urge for a radical reform of health systems' status quo.
Emmanouilidou, Maria
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Emergence and prospects of digital mediation in energy communities: ecosystem actors’ perspective
Energy, Sustainability and SocietyBackground Energy communities (ECs) hold out the promise of cleaner and more flexible energy systems through self-generation, demand response, and storage.
Khuram Shahzad +3 more
doaj +1 more source
Understanding Relationship: Maximizing the Effects of Science Coaching
Education Policy Analysis Archives, 2014 There is growing empirical evidence that instructional coaching can help teachers transfer their learning from professional trainings (e.g., new strategies) to classroom practice and that coaching promotes greater collaboration and reflection among ...
Ruth Anderson +2 more
doaj +1 more source
INNOVATIONS: Managing innovation and innovators
College & Research Libraries News, 1987 INNOVATIONS: Managing innovation and ...
openaire +2 more sources