Results 61 to 70 of about 154,198 (309)

Unraveling spatio-temporal rainfall variability in the Tlawng watershed, Mizoram under a tropical monsoon regime

open access: yesDiscover Geoscience
This study provides a comprehensive assessment of the spatiotemporal characteristics and long-term trends in rainfall across the Tlawng watershed in Mizoram, Northeast India, over a 40-year period (1984–2023).
Imanuel Lawmchullova   +7 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

INNOVATIVE TREND ANALYSIS METHODOLOGY IN LOGARITHMIC AXIS

open access: yesKonya Journal of Engineering Sciences, 2020
Future uncertainties of climate change cause people to worry, and therefore, in order toreduce the associated risks, scientific research methodologies are improved continuously. For instance,temperature raises as a result of carbon content increase cause variations in hydro-meteorological dataincluding evaporation, drought, precipitation, runoff, and ...
openaire   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Innovative trend analysis of annual rainfall in Iraq during 1980-2021

open access: yesJournal of Agrometeorology
Rainfall trend analysis is essential for managing water resources, agriculture, disaster management, and climate change research. The current study aims to examine annual rainfall variability and trend over 38 meteorological stations in Iraq during the ...
ALAA M. AL-LAMI   +2 more
doaj   +1 more source

Innovation policy of countries: analysis and key development trends

open access: yesInternational Economic Policy, 2023
The article comprehensively studies the essence of innovation policy and its impact on the competitiveness of countries. The types of innovation policy of countries are grouped by many criteria, in particular, by the strategy of innovation development, object of orientation, degree of regulation and direction.
Lesia Lyskova, Snizhana Podzihun
openaire   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Crop planning using innovative trend analysis of 62-years rainfall data

open access: yesThe Indian Journal of Agricultural Sciences
The success of climate-smart agriculture in high rainfall zone lies in understanding the rainfall trend and planning or modifying the cropping system for maximum yield.
S MANIVANNAN   +3 more
doaj   +1 more source

Advanced Rainfall Trend Analysis of 117 Years over West Coast Plain and Hill Agro-Climatic Region of India

open access: yesAtmosphere, 2020
In this paper, the rainfall trend of the West Coast Plain and Hill Agro-Climatic Region is analyzed for 117 years (1901–2017). This region is a globally recognized biodiversity hotspot and known for one of the highest rainfall receiving regions in India.
Atul Saini   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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