Results 71 to 80 of about 2,116,504 (346)

Unraveling spatio-temporal rainfall variability in the Tlawng watershed, Mizoram under a tropical monsoon regime

Discover Geoscience
This study provides a comprehensive assessment of the spatiotemporal characteristics and long-term trends in rainfall across the Tlawng watershed in Mizoram, Northeast India, over a 40-year period (1984–2023).
Imanuel Lawmchullova, Joseph Lalngaihawma, A. Lozaanba Khumbah, Lal Rinkimi, Vishwambhar Prasad Sati, Benjamin L. Saitluanga, Gyanendra Konthoujam, Bobby Beingachhi   +7 more
doaj   +1 more source

Realising Potential: Disability Confidence Builds Better Business [PDF]

, 2007
[Excerpt] ‘Realising potential’ sets out the latest thinking on how disabled people contribute to business success and how business, in the UK and globally, benefits from disability confidence.
Scott-Parker, Susan, Suter, Rhiannon, Zadek, Simon   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

INNOVATIVE TREND ANALYSIS METHODOLOGY IN LOGARITHMIC AXIS

Konya Journal of Engineering Sciences, 2020
Future uncertainties of climate change cause people to worry, and therefore, in order toreduce the associated risks, scientific research methodologies are improved continuously. For instance,temperature raises as a result of carbon content increase cause variations in hydro-meteorological dataincluding evaporation, drought, precipitation, runoff, and ...
openaire   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Innovation policy of countries: analysis and key development trends

International Economic Policy, 2023
The article comprehensively studies the essence of innovation policy and its impact on the competitiveness of countries. The types of innovation policy of countries are grouped by many criteria, in particular, by the strategy of innovation development, object of orientation, degree of regulation and direction.
Lesia Lyskova, Snizhana Podzihun
openaire   +1 more source

Trends and Design Relating literature to industry practice [PDF]

, 2008
In a crowded market place, where technology and functionality are not enough to differentiate a product from its competitors, the product’s appearance is a major driver of consumer preference.
Eckert, Claudia, Moultrie, James, Muir Wood, Andrew   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Crop planning using innovative trend analysis of 62-years rainfall data

The Indian Journal of Agricultural Sciences
The success of climate-smart agriculture in high rainfall zone lies in understanding the rainfall trend and planning or modifying the cropping system for maximum yield.
S MANIVANNAN, V KASTHURI THILAGAM, RAVINDRA YALIGAR, K N MANOJ   +3 more
doaj   +1 more source