Results 61 to 70 of about 169,462 (286)

Innovation Trends in NAFTA Countries: an Econometric Analysis of Patent Applications [PDF]

Journal of technology management & innovation, 2011
This paper analyzes innovation trends in North America Free Trade Agreement (NAFTA) countries by means of the number of patent applications during the period 1965 to 2008. Making use of patent data released by the World Intellectual Property Organization (WIPO) and the Network for Science and Technology Indicators (Red Iberoamericana de Ciencia y ...
José Carlos Rodríguez, Mario Gómez
openaire   +4 more sources

Crop planning using innovative trend analysis of 62-years rainfall data

The Indian Journal of Agricultural Sciences
The success of climate-smart agriculture in high rainfall zone lies in understanding the rainfall trend and planning or modifying the cropping system for maximum yield.
S MANIVANNAN, V KASTHURI THILAGAM, RAVINDRA YALIGAR, K N MANOJ   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Bibliometric Analysis of Organizational Innovation Trends

International Research Journal of Multidisciplinary Scope
In the current era, where technology is developing rapidly, and people's lifestyles are changing along with the times, organizations are required to be able to survive and develop to innovate. Innovation in organizations is implemented after the organization has conducted comprehensive research covering the internal and external conditions of the ...
Feira Aprilia Rosanti, Ika Nurul Qamari, null Arni Surwanti   +2 more
openaire   +1 more source

Trend analysis of monthly streamflows using Şen’s innovative trend method

, 2018
Analiza trenda srednjih mjesečnih strujanja je neophodna za bolje upravljanje vodama i planiranje. U ovom su istraživanju korišteni: Mann-Kendallova test (MK), Senova metoda i Şenova inovativna metoda trendova (ITM) kako bi se ispitali mogući trendovi ...
Kişi, Özgür, Richarde Marques da Silva, Zounemat-Kermani, Mohammad, Özgür Kişi, Guimarães Santos, Celso Augusto, Celso Augusto Guimarães Santos, Mohammad Zounemat-Kermani, Ö. Kişi, Marques da Silva, Richarde, M. Zounemat-Kermani, C. A. G. Santos, R. M. da Silva   +11 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Advanced Rainfall Trend Analysis of 117 Years over West Coast Plain and Hill Agro-Climatic Region of India

Atmosphere, 2020
In this paper, the rainfall trend of the West Coast Plain and Hill Agro-Climatic Region is analyzed for 117 years (1901–2017). This region is a globally recognized biodiversity hotspot and known for one of the highest rainfall receiving regions in India.
Atul Saini, Netrananda Sahu, Pankaj Kumar, Sridhara Nayak, Weili Duan, Ram Avtar, Swadhin Behera   +6 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Long-term trends and characterization of temperature and precipitation over Southwest Ethiopia and their hydro-climatic event implications

Discover Sustainability
Climate variability is a significant driver of global change and a threat to societies worldwide. Learning from past climatic patterns provides the foundation for building a resilient and sustainable future.
Bereket Abera Bedada, Wakjira Takala Dibaba, Megersa Kebede Leta, Chali Dereje Kitila, Million Ebba Bote, Tamene Adugna Demisssie   +5 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source