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The Antecendents Of Innovative Work Behavior: Concepts And Dimensions [PDF]

The study aims of this article is to propose a definition, identify dimensions and concepts of innovative behavior in lecturers. Innovative work behavior means all lecturer behavior regarding ideas in general, promotion and implementation of new ideas ...
jurnal, mimin, Intan Fauzi
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Studi Literatur: Innovative work behavior [PDF]

Innovative work behavior (IWB) merupakan elemen krusial bagi organisasi untuk menciptakan keunggulan kompetitif di tengah persaingan bisnis yang ketat.
Indah Permatasari Cahyaputri, Fajrianthi
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In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Leadership as a determinant of innovative behaviour [PDF]

In knowledge-intensive services innovative behaviour of co-workers is a critical success factor. In sectors like consultancy, research and architecture the nature of the work implies that projects are never alike.
Jeroen de Jong, Deanne den Hartog
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Autonomy Constrained: The Dynamic Interplay Among Job Autonomy, Work Engagement, and Innovative Behavior Under Performance Pressure

This study examines how performance pressure influences the complex relationships between job autonomy and critical employee outcomes in contemporary organizations.
Kim, Yong Cheol, Jang, Eunmi, Eunmi Jang, Yong Cheol Kim   +3 more
core   +1 more source

Empowering Innovation: The Role of Digital Leadership in Shaping Gen Z and Gen Y Performance with Creativity as a Moderator

Jurnal Manajemen Teori dan Terapan
Objective: This study develops a quantitative model that integrates digital leadership, innovative work behavior, and employee performance, while also examining the moderating effect of creativity from the perspective of Upper Echelons Theory.
Harris Prasetya Rahmandika, Yusuf Akbar Santoso, Dilla Imani, Nuri Herachwati   +3 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

How can servant leadership arouse to innovative work behavior? [PDF]

, 2022
This study examined the role of servant leadership in encouraging innovative work behavior of civil servants through increased employee engagement. This study used a quantitative method   by distributing   a   list   of   questions   to 116 ...
Widiastuti, Fitri, Amin, Shofia, Adriani, Zulfina   +2 more
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