Results 61 to 70 of about 115,892 (314)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
SMEs innovation and job creation potential in the shadow economy context [PDF]
, 2010 The presented paper treats about the ability of creating new jobs by innovative SMEs in Poland in the age of a deep transformation of the Polish economy. The authors try to verify the concept of B. A.
Głodek Paweł, Stawasz Edward
core +2 more sources
Innovating Firms and Aggregate Innovation [PDF]
Journal of Political Economy, 2002 We develop a parsimonious model of innovation to confront firmlevel evidence. It captures the dynamics of individual heterogeneous firms, describes the behavior of an industry with firm entry and exit, and delivers a general equilibrium model of technological change.
Klette, Tor Jakob, Kortum, Samuel
openaire +6 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
PLoS ONE, 2023 This study proposes a multilevel conceptual framework for a deeper understanding of the relationship between employee well-being and innovativeness. We overview 49 years of well-being research [1972-2021] and 54 years of research on innovativeness [1967 ...
Yousif Elsamani +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Green consumption: the role of perceived symbolic value and personal innovativeness [PDF]
Journal of Responsible Production and ConsumptionPurpose – This study aims to explore the relationship between personal innovativeness, perceived symbolic value and green purchase intentions within the context of sustainable consumption.
Albert Hasudungan +1 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
ENHANCED MANAGEMENT TOOLS FOR DEVELOPING ENTERPRISE INNOVATIVENESS
Research on Enterprise in Modern Economy Theory and Practice, 2018 Sustainable socio-economic development of a country depends on the competitiveness of enterprises, a key factor of which is continuous development of innovativeness.
Alena Apiakun
doaj +1 more source
Modeling innovation: determinants of innovativeness and the impact of innovation on firm performance [PDF]
, 2008 The objective of this paper is to report on the method, analysis, and conclusions concerning two research questions formulated as: What are the determinants of innovation at firm level?” and “what is the impact of innovation on firm performance?” The ...
Alpkan, Lutfihak +7 more
core +1 more source