Results 71 to 80 of about 35,652 (254)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Market Orientation, Innovativeness, and Performance of Food Companies [PDF]
Food processors have seen escalating levels of competition over the past three decades. An underlying objective of this research is to gain a greater understanding of how food companies thrive in the face of this increased competition.
Johnson, Aaron J. +2 more
core
What contributes to individual innovativeness? A multilevel perspective
International Journal of Innovation Studies, 2019 It is well-established that individual innovativeness is an indispensable quality for employees working in a variety of workplace environments. However, the interaction between the psychological and organizational factors influencing innovativeness ...
Tahani Z. Aldahdouh +2 more
doaj +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Methodology and tools of enterprise innovativeness evaluation [PDF]
Marketing i Menedžment Innovacij, 2015 The aim of the article. The aim of the article is to analyse critically the existing approaches to enterprise innovativeness evaluation, these approaches additions and organizing in order to justify the research methodology and develop tools for integral
L.O. Ligonenko
doaj
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
, 2016 Artikkeliväitöskirja. Sisältää yhteenveto-osan ja neljä artikkelia.Article dissertation. Contains an introduction part and five articles.This study examined ethical organisational culture, consisting of ethical organisational virtues, and organisational
Riivari, Elina
core +1 more source
Relationship between Nursing Informatics Competency and Innovativeness among Qualified Nurses
Evidence-Based Nursing ResearchContext: Nursing informatics is an important quality resource for patient care, which in effect promotes, enhances, and increases the organization's growth and influences the innovativeness level of the individuals.
Farida M. Hassona, Aziza Z. F. Ali
doaj +1 more source
Market orientation vs. inovativeness of SMEs of Podlaskie province
Business: Theory and Practice, 2015 This research aims to examine the impact of marketing orientation on the innovation level among Small and Medium Size (SMEs) from Podlaskie Province.
Joanna Ejdys
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source