Results 71 to 80 of about 115,892 (314)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

What contributes to individual innovativeness? A multilevel perspective

open access: yesInternational Journal of Innovation Studies, 2019
It is well-established that individual innovativeness is an indispensable quality for employees working in a variety of workplace environments. However, the interaction between the psychological and organizational factors influencing innovativeness ...
Tahani Z. Aldahdouh   +2 more
doaj   +1 more source

European Union Entrepreneurship and Innovativeness Support Policy for Businesses [PDF]

open access: yes, 2012
To a great extent, growth in entrepreneurship and innovativeness as significant factors in the economic development of Europe and Poland is dependent on the elimination of administrative barriers for companies and the introduction of the facilitating of ...
Wysokińska, Zofia
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Relationship between Nursing Informatics Competency and Innovativeness among Qualified Nurses

open access: yesEvidence-Based Nursing Research
Context: Nursing informatics is an important quality resource for patient care, which in effect promotes, enhances, and increases the organization's growth and influences the innovativeness level of the individuals.
Farida M. Hassona, Aziza Z. F. Ali
doaj   +1 more source

Methodology and tools of enterprise innovativeness evaluation [PDF]

open access: yesMarketing i Menedžment Innovacij, 2015
The aim of the article. The aim of the article is to analyse critically the existing approaches to enterprise innovativeness evaluation, these approaches additions and organizing in order to justify the research methodology and develop tools for integral
L.O. Ligonenko
doaj  

Communities, Knowledge, and Innovation: Indian Immigrants in the US Semiconductor Industry [PDF]

open access: yes
This paper investigates the influence of technological, geographic, and ethnic communities on the innovativeness of Indian inventors. We study Indian inventors in the semiconductor industry in the US and examine their patenting profiles between 1975 and ...
Anupama Phene, Paul Almeida, Sali Li
core  

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