Results 91 to 100 of about 26,330 (311)

Innovativeness of nurse leaders

open access: yes, 2011
The purpose of the present study was to describe the innovativeness and the rate of adoption of change among chief nursing officers (CNOs) of acute care hospitals, and explore the difference in the innovativeness of CNOs of Magnet hospitals vs.
Clement-O'Brien, Karen   +7 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Methodology and tools of enterprise innovativeness evaluation [PDF]

open access: yesMarketing i Menedžment Innovacij, 2015
The aim of the article. The aim of the article is to analyse critically the existing approaches to enterprise innovativeness evaluation, these approaches additions and organizing in order to justify the research methodology and develop tools for integral
L.O. Ligonenko
doaj  

Regional Factors and Innovativeness - An Empirical Analysis of Four German Industries [PDF]

open access: yes
A growing body of work emphasizes the importance of regional factors for regional innovativeness. In this paper, about seventy variables approximating the social-economic characteristics of regions are aggregated to twelve regional factors.
Thomas Brenner, Tom Broekel
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The impact of structural capital on the firm Innovativeness, the Galician Northern Portugal automotive industries reality [PDF]

open access: yes
The intellectual capital is increasingly considered a major issue on the management and organization research and a source of competitive advantage.
Pedro Figueroa   +2 more
core  

Consumer Innovativeness: Literature Review and Measurement Scales

open access: yes, 2018
Consumer innovativeness is the degree to which the innovative is received independently. Innovativeness is also defined as the degree to which individuals (other adoption units) adopt new ideas faster than other members in a system.
Kuswati, R, ., Irmawati
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Organisational innovativeness : the role of strategic orientation and environmental scanning

open access: yes, 2012
This study examined the effects of strategic orientation and environmental scanning on a firm’s propensity to innovate (organisational innovativeness).
Murray, Jennifer
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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