Results 91 to 100 of about 115,892 (314)
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Market orientation vs. inovativeness of SMEs of Podlaskie province
Business: Theory and Practice, 2015 This research aims to examine the impact of marketing orientation on the innovation level among Small and Medium Size (SMEs) from Podlaskie Province.
Joanna Ejdys
doaj +1 more source
The impact of structural capital on the firm Innovativeness, the Galician Northern Portugal automotive industries reality [PDF]
The intellectual capital is increasingly considered a major issue on the management and organization research and a source of competitive advantage.
Carlos Maria Jardon +2 more
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Vertical and horizontal technology transfer and firm innovativeness1
Studia i Materiały, 2018 The paper discusses the relationship between vertical and horizontal technology transfer and firms innovativeness. The main aim of the survey is to determine the relationship between vertical and horizontal technology transfer and innovativeness in ...
Karina Sachpazidu-Wójcicka
doaj +1 more source
Locational Conditions, Cooperation, and Innovativeness: Evidence from Research and Company Spin-offs [PDF]
This paper has two goals. First, it analyzes the extent to which the innovativeness of spin-offs, either born from a research facility or from another company, is influenced by locational conditions.
Andreas Stephan, Anna Lejpras
core
What are the determinants leading to innovation in manufacturing firms [PDF]
, 2013 In this paper, a comprehensive model of innovation determinants is analyzed based on empirical data gathered from 184 manufacturing firms located in the Northern Marmara region in Turkey.
Alpkan, Lutfihak +7 more
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Performance measurement procedures that support innovativeness rather than hamper it [PDF]
, 2004 This paper addresses the contemporary challenges in increasing firm-level innovativeness and developing appropriate performance metrics. The authors discuss these challenges and provide a literature review on the innovation enhancing factors in service ...
Blomqvist, Kirsimarja +4 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source