Results 101 to 110 of about 115,892 (314)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A Summary Assessment of Innovativeness of The New Member States of The European Union

open access: yesComparative Economic Research, 2017
This paper attempts to assess the level of innovativeness of the economies of the ‘new’ EU member states1 in the years 2008–2015, with particular attention paid to the position of the Polish economy.
Edyta Dworak, Maria Magdalena Grzelak
doaj   +1 more source

The innovativeness of the Finnish high technology firms – The role of internal factors, cooperation, and the mobility of labour [PDF]

open access: yes
Innovation is the driving force of the economy and it is the most important factor to the competitiveness of firms. Firms' capability to innovate, introduce new products to the market and develop new production methods has a significant effect on their ...
Jaakko Simonen
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

The Influence of Customer Perceived Restaurant Innovativeness (CPRI) of Meatball Restaurants on Brand Love and Brand Loyalty

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
The highly competitive landscape among food and beverage entrepreneurs in Indonesia compels brands to compete aggressively to attract and retain customers.
Qorina Firkiana   +2 more
doaj  

On the Marshall - Jacobs Controversy It takes two to tango [PDF]

open access: yes
The literature is inconclusive as to whether Marshallian specialization or Jacobian diversification externalities favour regional innovativeness. The specialization argument poses that regional specialization towards a particular industry improves ...
Cees van Beers, Gerben van der Panne
core  

Innovativeness of Small and Medium Enterprises as a Means to Increase their Market Competitiveness [PDF]

open access: yes, 2013
Konkurencyjność małych i średnich przedsiębiorstw jest ściśle powiązana z możliwością wprowadzania w nich innowacji. Zagadnienia te są częścią omawianej w artykule analizy opartej na badaniach ankietowych oraz rozmowach, przeprowadzonych w losowo ...
Mertl, Jan
core  

One size does (obviously not) fit all: Using product attributes for wine market segmentation [PDF]

open access: yes, 2017
The intense competition affecting the wine industry in recent decades has forced wineries and retailers to reshape their marketing strategies on the basis of consumer preferences.
Chrysochou, Polymeros   +4 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Effect of corruption and political instability on enterprises’ innovativeness in Ethiopia: pooled data based

open access: yesJournal of Innovation and Entrepreneurship, 2019
The aim of this study is to investigate the effects of corruption and political instability on Ethiopian enterprises’ innovativeness based on pooled data from 644 and 848 enterprises (manufacturing, retailing, and non-retailing services) surveyed in 2011
Arega Shumetie, Mulugeta Damie Watabaji
doaj   +1 more source

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