Results 111 to 120 of about 26,330 (311)

Regional Innovativeness Strategies And Their Impact On Innovativeness Of Provinces In Poland. A Spatio-temporal Analysis [PDF]

open access: yes, 2014
Regional Innovation Strategies (RIS) have existed in Poland for almost ten years and in this period they have been developed, accepted and implemented in all provinces.
Jan Kowalik, Kowalik, Jan
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A Summary Assessment of Innovativeness of The New Member States of The European Union

open access: yesComparative Economic Research, 2017
This paper attempts to assess the level of innovativeness of the economies of the ‘new’ EU member states1 in the years 2008–2015, with particular attention paid to the position of the Polish economy.
Edyta Dworak, Maria Magdalena Grzelak
doaj   +1 more source

TECHNOLOGICAL OPINION LEADERSHIP: PERAN DARI PERSONAL INNOVATIVENESS, GADGET LOVE, DAN TECHNOLOGICAL INNOVATIVENESS, DI SURAKARTA [PDF]

open access: yes, 2017
ABSTRAK TECHNOLOGICAL OPINION LEADERSHIP: PERAN DARI PERSONAL INNOVATIVENESS, GADGET LOVE, DAN TECHNOLOGICAL INNOVATIVENESS, DI SURAKARTA KHARISMA NUR AZIZAH F0213058 Penelitian ini bertujuan untuk (1) menganalisis pengaruh antara personal innovativeness
AZIZAH, KHARISMA NUR
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The mediator role of organizational innovativeness between organizational culture and organizational effectiveness

open access: yes, 2014
Organizational culture and organizational innovativeness are viewed as important factors for improving the organizational effectiveness in institutions of higher education.
Lope Pihie, Zaidatol Akmaliah   +3 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Market Orientation, Innovativeness, and Performance of Food Companies

open access: yes
Food processors have seen escalating levels of competition over the past three decades. An underlying objective of this research is to gain a greater understanding of how food companies thrive in the face of this increased competition.
Johnson, Aaron J.   +2 more
core  

Innovativeness as an Enssential Part of Entrepreneurial Training in Developing the Competitive Advantage: Terengganu Creative Industry

open access: yes, 2011
Basically the main objective of this study is to measure the significance of entrepreneurial training of innovativeness toward the competitive advantage in Terengganu creative industry This paper will look into the influence of innovativeness in four
Dr Mohd Shaladdin Muda   +2 more
core  

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