Results 11 to 20 of about 131,372 (308)

Is iNOS Beginning to Smoke? [PDF]

open access: yesCell, 2011
Inducible nitric oxide synthase (iNOS) helps drive numerous inflammatory disorders, but its inhibition has not had therapeutic success. Now Seimetz et al. (2011) make a case for inhibiting iNOS in an effort to treat one of the world's leading causes of death-chronic obstructive pulmonary disease.
Nathan, Carl, Carl Nathan
openaire   +4 more sources

The INOS Learning Design Framework:Fostering the Educational Value of Open Science, Citizen Science and Open Innovation Activities [PDF]

open access: yes, 2020
The document corresponds to O2A3 of the INOS Project. The INOSProject aims to enhance the impact of OS/CS/OI activities by offeringpedagogical support to HEIs and other activity ...
Teo, Elisha Anne; id_orcid
core   +3 more sources

iNOS-KO rats show slow clearance of S. japonicum, exacerbated pathological responses and increased morbidity.

open access: yes, 2022
Wildtype (WT) and iNOS knock-out (KO) rats were infected with 200 S. japonicum cercariae, parasites were perfused from the portal tract at 1, 4- and 7-weeks post-infection and counted under a stereoscopic microscope.
Jia Shen (1828945)   +6 more
core   +1 more source

A Hepatocyte-to-Stellate Cell Axis Couples Alternate-Day Fasting to Liver Fibrosis Resolution via ATG7 S-Nitrosylation. [PDF]

open access: yesAdv Sci (Weinh)
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Wang X   +17 more
europepmc   +2 more sources

Bridelia ferruginea Produces Anti-neuroinflammatory Activity through Inhibition of Nuclear Factor-kappa B and p38 MAPK Signalling [PDF]

open access: yes, 2012
Bridelia ferruginea is commonly used in traditional African medicine (TAM) for treating various inflammatory conditions. Extracts from the plant have been shown to exhibit anti-inflammatory property in a number of in vivo models.
Aderogba, Mutallib A.   +6 more
core   +1 more source

Thymoquinone-PLGA-PVA Nanoparticles Ameliorate Bleomycin-Induced Pulmonary Fibrosis in Rats via Regulation of Inflammatory Cytokines and iNOS Signaling

open access: yesAnimals, 2019
Pulmonary fibrosis is considered one of the most chronic interstitial illnesses which are not easily treated. thymoquinone’s (TQ) benefits are still partly problematic due to poor water solubility; therefore, it was loaded onto PLGA-PVA carriers ...
Sultan A. M. Saghir   +8 more
doaj   +1 more source

Chemometrics-Assisted Identification of Anti-Inflammatory Compounds from the Green Alga Klebsormidium flaccidum var. zivo

open access: yesMolecules, 2020
The green alga Klebsormidium flaccidum var. zivo is a rich source of proteins, polyphenols, and bioactive small-molecule compounds. An approach involving chromatographic fractionation, anti-inflammatory activity testing, ultrahigh performance liquid ...
Shi Qiu   +8 more
doaj   +1 more source

Seasonal Water Mass Transformation in the Eastern Indian Ocean from In Situ Observations

open access: yesAtmosphere, 2023
The Eastern Indian Ocean (EIO) is one of the eastern boundary areas, which control currents circulation and atmospheric dynamics. This research mainly aimed to identify and analyze the water mass transformation in the EIO.
Noir P. Purba   +4 more
doaj   +1 more source

THE ROLE OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES IN INHIBITION MACROPHAGES NITROGEN MONOXIDE (NO) SYNTHESIS

open access: yesИнфекция и иммунитет, 2018
The protective role of macrophages closely related to the production of bactericidal molecules, in which nitrogen monoxide (NO) play an  important role.
E. A. Starikova   +6 more
doaj   +1 more source

Determination of some oxidative stress and inflammation markers in serum, blood and csf in cattle with head-eye form of malignant catarrhal fever [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2017
The aim of this study was to determine changes in total sialic acid (TSA), malondialdehyde (MDA), nitric oxide (NO), inducible nitric oxide synthase (iNOS) and endothelial nitric oxide synthase (eNOS) levels on sera and CSF and reduced glutathione (GSH ...
Ekin Emre ERKILIÇ   +8 more
doaj   +1 more source

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