Nitric Oxide Regulates Neurogenesis in the Hippocampus following Seizures [PDF]
, 2015 Hippocampal neurogenesis is changed by brain injury. When neuroinflammation accompanies injury, activation of resident microglial cells promotes the release of inflammatory cytokines and reactive oxygen/nitrogen species like nitric oxide (NO).
Araújo, Inês +4 more
core +11 more sources
Sleep-wake sensitive mechanisms of adenosine release in the basal forebrain of rodents : an in vitro study [PDF]
, 2013 Adenosine acting in the basal forebrain is a key mediator of sleep homeostasis. Extracellular adenosine concentrations increase during wakefulness, especially during prolonged wakefulness and lead to increased sleep pressure and subsequent rebound sleep.
A Alonso +72 more
core +14 more sources
Upregulation of inducible NO synthase by exogenous adenosine in vascular smooth muscle cells activated by inflammatory stimuli in experimental diabetes [PDF]
, 2016 BACKGROUND: Adenosine has been shown to induce nitric oxide (NO) production via inducible NO synthase (iNOS) activation in vascular smooth muscle cells (VSMCs). Although this is interpreted as a beneficial vasodilating pathway in vaso-occlusive disorders,
Cignarella, Andrea +4 more
core +2 more sources
Nitric oxide from inflammatory origin impairs neural stem cell proliferation by inhibiting epidermal growth factor receptor signaling [PDF]
, 2014 Neuroinflammation is characterized by activation of microglial cells, followed by production of nitric oxide (NO), which may have different outcomes on neurogenesis, favoring or inhibiting this process.
Alvarez-Buylla +85 more
core +2 more sources
The role of self-interacting right-handed neutrinos in galactic structure [PDF]
, 2015 It has been shown previously that the DM in galactic halos can be explained by a self-gravitating system of massive keV fermions (`inos') in thermodynamic equilibrium, and predicted the existence of a denser quantum core of inos towards the center of ...
Argüelles, C. R. +3 more
core +2 more sources
Male gender predisposes to development of endotoxic shock in the rat [PDF]
, 2000 Objective: After intravenous (i.v.) injection of lipopolysaccharide (LPS) macrophages release nitric oxide (NO) due to the expression of the inducible NO synthase (iNOS).
Baylis, C. +7 more
core +1 more source
Evaluation of the effect of administration of Tadalafil on Gentamicin-induced nephrotoxicity in rats [PDF]
Egyptian Journal of Medical Research, 2022 Background: Gentamicin (GNT) is a highly effective aminoglycoside antibiotic that is commonly used to treat life-threatening bacterial infections.
Ekhlas Mohammed +3 more
doaj +1 more source
Animals, 2019 Pulmonary fibrosis is considered one of the most chronic interstitial illnesses which are not easily treated. thymoquinone’s (TQ) benefits are still partly problematic due to poor water solubility; therefore, it was loaded onto PLGA-PVA carriers ...
Sultan A. M. Saghir +8 more
doaj +1 more source
Determination of some oxidative stress and inflammation markers in serum, blood and csf in cattle with head-eye form of malignant catarrhal fever [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017 The aim of this study was to determine changes in total sialic acid (TSA), malondialdehyde (MDA), nitric oxide (NO), inducible nitric oxide synthase (iNOS) and endothelial nitric oxide synthase (eNOS) levels on sera and CSF and reduced glutathione (GSH ...
Ekin Emre ERKILIÇ +8 more
doaj +1 more source
Инфекция и иммунитет, 2018 The protective role of macrophages closely related to the production of bactericidal molecules, in which nitrogen monoxide (NO) play an important role.
E. A. Starikova +6 more
doaj +1 more source