Is iNOS Beginning to Smoke? [PDF]
Cell, 2011 Inducible nitric oxide synthase (iNOS) helps drive numerous inflammatory disorders, but its inhibition has not had therapeutic success. Now Seimetz et al. (2011) make a case for inhibiting iNOS in an effort to treat one of the world's leading causes of death-chronic obstructive pulmonary disease.
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Cancer Management and Research, 2023 Liu S, Jiang J, Huang L, et al. Cancer Manag Res. 2019;11:8005–8022. We, the Editors and Publisher of Cancer Management and Research, have retracted the published article. Concerns were raised following the authors request to correct Figure 4.
Liu S +11 more
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Pharmacological investigation of oxadiazole derivatives in Alzheimer’s disease: Modulation of oxidative stress, neuroinflammation, and iNOS signaling [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by deposition of amyloid-beta (Aβ) aggregates. Aβ peptides alter synaptic function and produce neuroinflammation.
Amber Mahmood Minhas +4 more
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Endothelial cell-derived SSAO can increase MLC20 phosphorylation in VSMCs
Open Life Sciences, 2021 Vascular hyporesponsiveness in the shock decompensation period is an important factor leading to death. Myosin light chain 20 (MLC20) is the main effector protein that regulates vascular reactivity.
Zhang Yuxing +5 more
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Protective effect of Cupressus macrocarpa and Dioon edule against gentamicin-induced nephrotoxicity in rats [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2020 Context: It has been reported that Cupressus macrocarpa Hartw. ex Gordon (Cupressaceae) and Dioon edule Lindl. (Zamiaceae) contain compounds with antioxidant and anti-inflammatory effects; therefore, they may exert a nephroprotective effect.
Ghada Mohammad Al-Ashmawy +1 more
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Preconditioning of isoflurane on spinal cord ischemia can increase the number of inducible nitric oxide synthase-expressing motor neurons in rat [PDF]
Korean Journal of Anesthesiology, 2010 BackgroundSpinal cord ischemia with resulting paraplegia remains one of the most common complications after repair of thoracoabdominal aortic aneurysms or dissection.
Yun-Hee Sung +6 more
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Frontiers in Artificial IntelligenceThe Fourth Industrial Revolution (4IR) has accelerated the adoption of Artificial Intelligence (AI) across knowledge intensive sectors, yet its integration in Library and Information Services (LIS) within resource constrained educational environments ...
Inos Chibidi, Logic Magwa
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Maslinic Acid Ameliorates Inflammation via the Downregulation of NF-κB and STAT-1
Antioxidants, 2020 Maslinic acid (MA), a natural compound of the triterpenoid group derived from olive, prevents the generation of pro-inflammatory cytokines and oxidative stress.
Wonhwa Lee +3 more
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Expression of Inducible Nitric Oxide Synthase in Keratocystic Odontogenic Tumour and Variants of Ameloblastoma – A Comparative Study [PDF]
Journal of Clinical and Diagnostic Research, 2014 Introduction: The odontogenic keratocyst (OKC) is a histopathologiocally and behaviourally unique and specific entity. It is the most aggressive and recurrent of all the cysts and shows characteristics resembling both cyst and a tumour.
Diana.H +4 more
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Indexes of nitric oxide system in experimental antiphospholipid syndrome [PDF]
The Ukrainian Biochemical Journal, 2020 Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence of antibodies to negatively charged membrane phospholipids (aPL).
O. Z. Yaremchuk +5 more
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