The effects of severe hypoxia on nitric oxide parameters in hypoxia-tolerant rodent: nannospalax nehringi [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2018 Blind mole rats (BMRs) are solitary rodents which are tolerant to severe hypoxia. The aim of this study is to reveal the changes in nitric oxide (NO) and nitric oxide enzymes (NOS), which are involved in many physiological and pathological processes ...
Barış YILDIZ +6 more
doaj +1 more source
Seasonal Water Mass Transformation in the Eastern Indian Ocean from In Situ Observations
Atmosphere, 2023 The Eastern Indian Ocean (EIO) is one of the eastern boundary areas, which control currents circulation and atmospheric dynamics. This research mainly aimed to identify and analyze the water mass transformation in the EIO.
Noir P. Purba +4 more
doaj +1 more source
Bridelia ferruginea Produces Anti-neuroinflammatory Activity through Inhibition of Nuclear Factor-kappa B and p38 MAPK Signalling [PDF]
, 2012 Bridelia ferruginea is commonly used in traditional African medicine (TAM) for treating various inflammatory conditions. Extracts from the plant have been shown to exhibit anti-inflammatory property in a number of in vivo models.
Aderogba, Mutallib A. +3 more
core +2 more sources
Supersymmetry and the LHC Inverse Problem [PDF]
, 2005 Given experimental evidence at the LHC for physics beyond the standard model, how can we determine the nature of the underlying theory? We initiate an approach to studying the "inverse map" from the space of LHC signatures to the parameter space of ...
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core +2 more sources
Endothelial cell-derived SSAO can increase MLC20 phosphorylation in VSMCs
Open Life Sciences, 2021 Vascular hyporesponsiveness in the shock decompensation period is an important factor leading to death. Myosin light chain 20 (MLC20) is the main effector protein that regulates vascular reactivity.
Zhang Yuxing +5 more
doaj +1 more source
Toll-Like Receptor 4 Modulates Small Intestine Neuromuscular Function through Nitrergic and Purinergic Pathways [PDF]
, 2017 Objective: Toll-like receptors (TLRs) play a pivotal role in the homeostatic microflora-host crosstalk. TLR4-mediated modulation of both motility and enteric neuronal survival has been reported mainly for colon with limited information on the role of ...
Cecilia Giulivi +12 more
core +3 more sources
Clinical, Cosmetic and Investigational Dermatology, 2023 Fei Wang,1– 3,* Jitao Liu,1– 3 Quan An,1– 4,* Yiming Wang,1– 3 Yang Yang,1– 3 Tong Huo,1– 3 Simin Yang,5 Ruijun Ju,5 Qianghua Quan1– 4 1Research and Development Department, Yunnan Baiyao Group Health Products Co., Ltd., Kunming, People’s Republic
Wang F +8 more
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A long-term "memory" of HIF induction in response to chronic mild decreased oxygen after oxygen normalization [PDF]
, 2007 Background Endothelial dysfunction (ED) is functionally characterized by decreased vasorelaxation, increased thrombosis, increased inflammation, and altered angiogenic potential, has been intimately associated with the progression and severity of ...
Ceriello, Antonio +6 more
core +3 more sources
Advanced Biology, EarlyView.HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang +6 more
wiley +1 more source
Maslinic Acid Ameliorates Inflammation via the Downregulation of NF-κB and STAT-1
Antioxidants, 2020 Maslinic acid (MA), a natural compound of the triterpenoid group derived from olive, prevents the generation of pro-inflammatory cytokines and oxidative stress.
Wonhwa Lee +3 more
doaj +1 more source