Results 71 to 80 of about 131,372 (308)
Beilstein Journal of Organic Chemistry, 2023 Six new compounds, including a tetralone 1, two xanthones 2 and 3, a flavan derivative 4, and two nor-diterpenoids 7 and 8, accompanied by two known flavan derivatives 5 and 6 and a known olefine acid (9) were isolated from whole bodies of Kronopolites ...
Yuan-Nan Yuan +5 more
doaj +1 more source
, 2014 Representative confocal images of single immunolabeling (IL) for iNOS (A) and its negative control, omitting the primary antibody (B) from whole-mounted retinas of quail embryos at 8 days of incubation.
José L. Marín-Teva (623508) +8 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source
Homocysteine induces iNOS and oxLDL accumulation in murine immune cells
Türk Biyokimya DergisiIncreased levels of homocysteine (Hcy) in the blood are considered to be a risk factor for atherosclerosis. Endothelial damage induced by Hcy can lead to deterioration of coronary, cerebral, and peripheral vascular beds, contributing to cardiovascular ...
Elma Yusuf +4 more
doaj +1 more source
, 2015 Effect of curcumin on mRNA expression and protein level of iNOS (A) RT-PCR of iNOS and β-actin (B) Densitometric scanning of iNOS mRNA after normalization with β-actin.
Laxmidhar Das (578450) +1 more
core +1 more source
Advanced Science, EarlyView.The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang +11 more
wiley +1 more source
A drug cocktail for protecting against ischemia-reperfusion injury
Frontiers in Bioscience-Landmark, 2020 Ischemia followed by reperfusion (I/R) of cardiomyocytes causes release of a large amount of inducible nitric oxide (NO) synthase (iNOS) followed by an increase of asymmetric dimethylarginine (ADMA).
Anna Krzywonos-Zawadzka +3 more
doaj +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Generation of iNOS/dystrophin double knockout mice.
, 2013 A, Outline of the breeding scheme. Dystrophin and iNOS heterozygous male (Dys, Y/4cv; iNOS, +/−) and female (Dys, wt/4cv; iNOS, +/−) mice were generated by crossing iNOS knockout mice with mdx4cv mice.
Jin-Hong Shin (309178) +2 more
core +1 more source
Brain function in iNOS knock out or iNOS inhibited (l-NIL) mice under endotoxic shock [PDF]
, 2014 BACKGROUND: Microcirculatory dysfunction due to excessive nitric oxide production by the inducible nitric oxide synthase (iNOS) is often seen as a motor of sepsis-related organ dysfunction. Thus, blocking iNOS may improve organ function.
Schweighöfer, Hanna +8 more
core +2 more sources