Results 151 to 160 of about 66,823 (327)

Cutting‐Edge Advancements in the Antibiotics‐Gut Microbiota‐Urinary Tumour Axis

open access: yesCell Proliferation, EarlyView.
Gut microbiota regulates urological tumors. Antibiotics induce dysbiosis, altering tumor progression/therapy: reducing carcinogen metabolism but impairing immunity. Specific bacteria enhance immune responses and combat endocrine resistance. Future research should unravel microbiota‐cancer links and develop microbiome‐targeted therapies to optimize ...
Jie Wang   +3 more
wiley   +1 more source

Adenosine-to-Inosine Editing of MicroRNA-487b Alters Target Gene Selection After Ischemia and Promotes Neovascularization

open access: yesCirculation Research, 2017
Rationale: Adenosine-to-inosine editing of microRNAs has the potential to cause a shift in target site selection. 2′-O-ribose-methylation of adenosine residues, however, has been shown to inhibit adenosine-to-inosine editing.
R. V. D. Kwast   +5 more
semanticscholar   +1 more source

Inhibition of inosine metabolism of the gut microbiota decreases testosterone secretion in the testis

open access: yesmSystems
Growing evidence indicates that gut microbiota is involved in the regulation of the host’s sex hormone levels, such as through interfering with the sex hormone metabolism in the intestine.
Lei Tang   +8 more
doaj   +1 more source

Influence of nonsteroid anabolic inosine on manifestation of the effects of dexamethasone on skeletal muscle of white rats

open access: yesБіологічні студії, 2012
In experiments on young rat females, it has been established, that the nonsteroid anabolic inosine caused in the case of complex application with dexamethasone the increasing of a specific fraction of slow or intermediate type of fibers in initially ...
V. V. Trush
doaj   +1 more source

Harnessing nucleotide metabolism and immunity in cancer: a tumour microenvironment perspective

open access: yesThe FEBS Journal, EarlyView.
This review explores how changes in nucleotide metabolism affect the tumour microenvironment and immune responses in cancer. Here, we discuss the dual role of nucleotide metabolism in promoting cancer cell growth and shaping immune suppression. We highlight how therapies targeting nucleotide pathways can enhance immunotherapy efficacy, offering new ...
Hadil Suleiman   +5 more
wiley   +1 more source

Inosine RNA modifications are enriched at the codon wobble position in mouse oocytes and eggs†

open access: yesBiology of Reproduction, 2019
Mammalian oocytes and eggs are transcriptionally quiescent and depend on post-transcriptional mechanisms for proper maturation. Post-transcriptional mRNA modifications comprise an important regulatory mechanism that can alter protein and miRNA ...
Pavla Brachova   +6 more
semanticscholar   +1 more source

Rapid, Diagnostic Test for Cardiac Ischemia [PDF]

open access: yes, 2017
Current methods to detect cardiac ischemia rely on biomarkers such as troponin. Elevated levels of troponin are observed hours after the cardiac event.
Contreras, Julio   +4 more
core   +2 more sources

Enzymic Synthesis of Xanthosine- and Guanosine-5-phosphate from Inosine-5-phosphate. [PDF]

open access: bronze, 1955
Ulf Lagerkvist   +3 more
openalex   +1 more source

Bacterial purine metabolism modulates C. elegans development and stress tolerance via DAF‐16

open access: yesThe FEBS Journal, EarlyView.
To investigate the impact of dietary components on animal growth, an Escherichia coli single‐gene deletion library was screened using the Caenorhabditis elegans growth model. Thirty‐four E. coli mutants were identified to delay worm development. Notably, E.
Min Feng   +3 more
wiley   +1 more source

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