Results 171 to 180 of about 44,397 (216)
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Vasoactivity of inosine in the rat

Pharmacological Research Communications, 1980
Summary Inosine increases the blood pressure in the rat independently of the autonomic nervous system. The mechanism of this hypertensive effect was investigated in 18 rats anesthetized with sodium pentobarbital. Inosine (0.01 M) infused at 0.03, 0.06, and 0.08 ml/min into the external jugular vein consistently caused a sustained, dose-dependent rise
R L, Prewitt, J M, Sullivan
openaire   +2 more sources

Inhibitors of inosinic acid dehydrogenase. 2-Substituted inosinic acids

Journal of Medicinal Chemistry, 1984
A series of 2-substituted inosine monophosphate (IMP) and inosine derivatives were synthesized and tested for inhibitory activity against IMP dehydrogenase from Escherichia coli. All of the IMP analogues that possessed electron-withdrawing substituents on the phenyl ring of a benzylthio group placed at the 2-position of IMP showed strong inhibition ...
C G, Wong, R B, Meyer
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Synthesis of Inosine Polyphosphates from Inosine 5’-Phosphate

Advanced Materials Research, 2014
Treatment of inosine 5’-phosphate (IMP) with 2,2’-dithiodianiline/triphenylphosphine provided an efficient method for the synthesis of inosine 5′-phosphoropiperidate under mild conditions. Inosine 5’-triphosphate (ITP) and inosine 5′-diphosphate (IDP) were efficiently synthesized from inosine 5’-phosphoropiperidate via the activation P(V)—N bond by 4,5-
Jian Sun, Shan Shan Gong, Qi Sun
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The reaction of inosine with formaldehyde

Experientia, 1964
Die Existenz einer Reaktion zwischen Formaldehyd und der sauren Iminogruppe von Inosin wird an Hand der dabei auftretenden pH-Erhohung sowie den Veranderungen der UV-Absorption gezeigt.
openaire   +2 more sources

Conversion of 5′-inosinic acid to inosine by Streptomyces aureus

Journal of Fermentation Technology, 1988
Abstract The production of inosine by microbial conversion of 5′-inosinic acid (IMP) was investigated. Among the various strains of Streptomyces and Bacillus tested, Streptomyces aureus NCIB 9803 was selected for the microbial conversion process due to its high IMP-degrading activity.
null Krung Hyun Sohn   +4 more
openaire   +1 more source

STABILITY OF INOSINIC ACID, INOSINE AND HYPOXANTHINE IN AQUEOUS SOLUTIONS

Journal of Food Science, 1972
The stability of inosinic acid. inosine and hypoxanthine in aqueous solutions at 90°C was studied. Inosinic acid, inosine and hypoxanthine were separated by ion exchange chromatography and spectrometrically estimated. Reaction rates in the region pH 2–12 were calculated.
J. DAVÍDEK, J. VELÍšEK, G. JANÍČEK
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INOSINE PRANOBEX

The Lancet, 1985
A J, Glasky   +3 more
openaire   +2 more sources

The Enzymatic Microestimation of Inosine, Adenosine and Inosinic Acid

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1971
E, Manoukian, G, Fawaz
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