Inosine-containing mRNA induces an innate immune response and is translated with lower efficiency
Inosine is a nucleoside formed by deamination of adenosine by adenosine deaminases acting on RNA (ADAR). ADAR editing activity is known to play a key role in modulating the host cell’s immune response to RNA. Here, we specifically study the effect of the
Bao, Caroline
core
Glutamine-dependent biosynthetic pathways fuel autoreactive T and B cells in Foxp3 deficiency-mediated disease. [PDF]
Zafar MA +11 more
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Moisture sorption and hydration dynamics in intrinsically hygroscopic hydrogels. [PDF]
Guan W +7 more
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EndoV does not measurably affect TadA-dependent A-to-I RNA editing in <i>Escherichia coli</i> under exponential-growth conditions in rich medium. [PDF]
Fargeon O, Bar-Yaacov D.
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Maternal separation-induced changes in breast milk fatty acid composition are associated with altered gut microbiota and serotonergic gene expression in neonatal mice. [PDF]
Mady EA +10 more
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From Gut Homeostasis to Colorectal Cancer: Spatial and Temporal Reprogramming of Microbial Inosine Signaling. [PDF]
Tomassini L +4 more
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Multi-omics profiling identifies inosine as a key metabolite associated with embryonic arrest in hydrosalpinx-associated infertility. [PDF]
Peng Y +10 more
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Efficacy and Safety of Fixed Dose Combination of Inosine Monophosphate, Agmatine Sulphate, and L-Carnosine (CGXNW) as Add-on Therapy for the Management of Spinal Cord Injury - A Randomized Controlled Clinical Trial. [PDF]
Kundnani V +4 more
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Correction to "Prophylactic supplementation with <i>Bifidobacterium infantis</i> or its metabolite inosine attenuates cardiac ischemia/reperfusion injury". [PDF]
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