Results 191 to 200 of about 86,294 (302)

Fragment-Based Approach to Targeting Inosine-5′-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis

open access: hybrid, 2018
Ana Trapero   +8 more
openalex   +1 more source

Role of the stage-regulated nucleoside transporter TbNT10 in differentiation and adenosine uptake in Trypanosoma brucei [PDF]

open access: yes, 2007
Al-Salabi   +25 more
core   +2 more sources

Absorption of pyrimidines, purines, and nucleosides by Co, Ni, Cu and Fe /III-montmorillonite /clay-organic studies XIII/ [PDF]

open access: yes
Absorption of pyrimidines, purines, and nucleosides by copper, nickel, cobalt, and iron ...
Brindley, G. W.   +2 more
core   +1 more source

Human Umbilical Cord Plasma Metabolomics Uncover Potential Metabolites for Combating Aging

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
Untargeted metabolomics reveals a unique cord plasma metabolic landscape versus adult. Age‐declining cord‐specific enriched metabolites are identified as antiaging candidates, with a 5‐compound formula validated in proof‐of‐experiments to extend lifespan and healthspan in human cells and C. elegans.
JiaYu Liu   +27 more
wiley   +1 more source

Age‐Dependent Metabolomic Signatures of Dietary Restriction in Mice

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
Elevated hepatic glutathione (GSH) and 3‐hydroxybutyrate (3‐HB) levels in all ages of mice demonstrate an enhanced protection against oxidative stress and improvement in energy metabolism during chronic dietary restriction (DR). However, high protein or muscle degradation in liver of young mice, and large accumulation of hepatic glycogen and excessive ...
Ji‐sue Lee   +4 more
wiley   +1 more source

The Differential Effects of Immunosuppressants on Hepatitis E Virus Replication and the Triggered Inflammatory Responses in Macrophages

open access: yesJournal of Viral Hepatitis, Volume 33, Issue 1, January 2026.
ABSTRACT Organ transplant recipients are at high risk of developing chronic infection when exposed to hepatitis E virus (HEV), which can rapidly progress to liver fibrosis and cirrhosis. Macrophages play a key role in the response to the infection and disease progression.
Jiahua Zhou   +4 more
wiley   +1 more source

Effects of Replacing Fish Meal With Plant Protein Sources in Diets With or Without Jack Mackerel Meal Inclusion on Growth Performance of Red Sea Bream (Pagrus major)

open access: yesAquaculture Nutrition, Volume 2026, Issue 1, 2026.
Due to stagnant production and high cost of fish meal (FM), feed nutritionists are seeking reliable and affordable alternatives. However, low‐FM diets often result in poor palatability, reduced feed consumption (FC), and impaired growth. This study investigates the effects of replacing FM with plant proteins in diets with or without jack mackerel meal (
Yu Jin Sim   +10 more
wiley   +1 more source

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