Results 301 to 310 of about 270,142 (371)

PI5P4K inhibitors: promising opportunities and challenges

open access: yesThe FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi   +16 more
wiley   +1 more source

The Vacuolar Inositol Transporter BvINT1;1 Contributes to Raffinose Biosynthesis and Reactive Oxygen Species Scavenging During Cold Stress in Sugar Beet. [PDF]

open access: yesPlant Cell Environ
Berg J   +14 more
europepmc   +1 more source

Epigenetic control of cell identities from epiblast to gastrulation

open access: yesThe FEBS Journal, EarlyView.
In this review, we present and contextualize current knowledge about the roles of epigenetic modifiers during the development of mouse epiblast to gastrulation stage. The epigenetic regulation of enhancer and promoter elements by DNA methylation, histone modifications, and chromatin accessibility in concert with lineage‐specific transcription factors ...
Katrin M. Schüle, Simone Probst
wiley   +1 more source

The effects of caffeine and adenosine on the microbiome and lipidome of the scalp

open access: yesInternational Journal of Cosmetic Science, EarlyView.
At 12 weeks, anti‐hair loss effects were evident with decreased Pseudomonas, Escherichia‐Shigella and Malassezia and increased Talaromyces and Cutibacterium. Lipid levels were impacted, correlating with Escherichia‐Shigella and Talaromyces. Abstract Hair loss is a complex multifactorial process.
Fengzhu Li   +10 more
wiley   +1 more source

Omics for searching plasma biomarkers associated with unfavorable COVID-19 progression in hypertensive patients. [PDF]

open access: yesSci Rep
Sánchez A   +10 more
europepmc   +1 more source

The PNH French Working Group Experience: Building a Strong Network of Cytometrists

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The PNH working group was created in 2010 to initiate a workshop on testing white blood cells to share international recommendations. Methods Thirty‐five French and Belgian laboratories equipped with 2‐ or 3‐laser cytometers applied three different panels with or without FLAER reagent in 305 samples.
Orianne Wagner‐Ballon   +9 more
wiley   +1 more source

MYPP trial: Myo-inositol supplementation to prevent pregnancy complications in women with polycystic ovary syndrome, study protocol for a multicenter, double-blind, randomized controlled trial

open access: yes
van der Wel AW   +30 more
europepmc   +1 more source

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