Results 351 to 360 of about 331,728 (400)

The inositol trisphosphate calcium channel is inactivated by inositol trisphosphate [PDF]

Nature, 1994
Activation of intracellular Ca2+ channels by inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) represents the initial Ca2+ mobilization step in response to many extracellular signals. Here we report that Ins(1,4,5)P3-induced channel activation in permeabilized hepatocytes is followed by a time-dependent inactivation, which is a direct consequence of ligand ...
Andrew P. Thomas, György Hajnóczky
openaire   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

A bioautographic method for the identification of inositol and inositol phosphate

Analytical Biochemistry, 1962
Abstract A bioautographic method, utilizing Saccharomyces carlsbergensis strain 4228, was shown to be capable of detecting and distinguishing between myoinositol, myoinositol 2-phosphate, and other derivatives of myoinositol. The method was shown to respond to as little as 1 μg inositol and is effective even in the presence of lipid hydrolyzates.
openaire   +3 more sources

General synthesis of inositols by hydrolysis of conduritol epoxides obtained biocatalytically from halogenobenzenes: (+)-D-chiro-inositol, allo-inositol, muco-inositol and neo-inositol

Journal of the Chemical Society, Perkin Transactions 1, 1993
Four of the nine isomeric inositols have been prepared by hydrolytic opening of epoxides derived from 3-halogenocyclohexa-3,5-diene-1,2-diol by further oxidation with potassium permanganate or by reduction of chiro-3-inosose (2L-2,3,6/4,5-pentahydroxycyclohexanone).
Martin Mandel, Tomas Hudlicky
openaire   +2 more sources

Alpha-lactalbumin Effect on Myo-inositol Intestinal Absorption: In vivo and In vitro.

Current Drug Delivery, 2018
BACKGROUND Myo-inositol is a natural molecule with important therapeutic applications and an impaired oral absorption may result in a reduced clinical effect. Aim of this study was to determine if the combined oral administration of α-lactalbumin and myo-
G. Monastra, Y. Sambuy, S. Ferruzza, D. Ferrari, G. Ranaldi   +4 more
semanticscholar   +1 more source

Metabolism and Function of myo-Inositol and Inositol Phospholipids

Annual Review of Nutrition, 1986
Alterations in the level of dietary inositol can significantly influence the concentration of free inositol and inositol-containing phospholipid in the circulation and in selected mammalian tissues and cells. The 1-stearoyl 2-arachidonyl molecular species that commonly predominates in cellular phosphoinositides may be of considerable importance for the
openaire   +2 more sources

Antagonistic Effect of Inositol Pentakisphosphate on Inositol Triphosphate Receptors

Biochemical and Biophysical Research Communications, 1996
We present evidence that inositol 1,3,4,5,6-pentakisphosphate acts as an antagonist of inositol triphosphate receptors in vitro by dampening the activity of Ca(2+)-mobilizing inositol phosphates. This antagonism bears physiological significance as cells maintain substantial quantities of this phosphoinositol in the cytosol, especially during cell ...
Pei Jung Lu, Woan-Ru Shieh, Ching Shih Chen, Ching Shih Chen   +3 more
openaire   +3 more sources

Multitarget Activities of Inositol and Inositol Hexakisphosphate

2020
Multiple health beneficial effects have been shown for inositol hexakisphosphate (IP6) and its parent compound myo-inositol (Ins) in animal and human studies. However, the most striking is their consistent and reproducible anticancer effect, actively investigated and demonstrated in various experimental models during the last decades.
openaire   +2 more sources

INOSITOL PHOSPHATE BIOCHEMISTRY

Annual Review of Biochemistry, 1992
PERSPECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 C ONVENTIONAL PHOSPHA TIDYLIN OSITOLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226 PHOSPHOLIPASE C . . . . . . . . . .
openaire   +3 more sources

An inositol phosphatide of peas

Archives of Biochemistry and Biophysics, 1960
Abstract Inositol phosphatide has been obtained from raw peas of all stages of maturity, excluding dry seed peas, after the peas were held in frozen storage (−17.8 °C.) for several months. The liberation is believed to be enzymic in nature. Peas which had been heat treated to inactivate enzymes yielded negligible amounts of inositol phosphatide ...
A.C. Wagenknecht, L.M. Lewin
openaire   +3 more sources

From Myo-inositol to D-chiro-inositol molecular pathways.

European Review for Medical and Pharmacological Sciences, 2021
A. K. Kiani, S. Paolacci, A. Calogero, R. Cannarella, G. Di Renzo, S. Gerli, C. Della Morte, G. Busetto, E. De Berardinis, F. del Giudice, L. Stuppia, F. Facchinetti, S. Dinicola, M. Bertelli   +13 more
semanticscholar   +1 more source