Results 111 to 120 of about 58,268 (235)
Communicative & Integrative Biology, 2010 Autosomal dominant polycystic kidney disease (ADPKD) arises as a consequence of mutations of the genes PKD1 and PKD2, encoding respectively the integral membrane proteins polycystin-1 and polycystin-2 (TRPP2), resulting in a disturbance in intracellular ...
Eva Sammels +6 more
doaj +1 more source
Mechanisms underlying gastric antral slow waves – a human perspective
The Journal of Physiology, EarlyView.
Dirk F. van Helden
wiley +1 more source
Patterns of Acute Liver Injury and Post‐Acute Liver Sequelae of COVID‐19
Liver International Communications, Volume 7, Issue 3, September 2026.ABSTRACT Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is known to cause acute liver injury (ALI) in COVID‐19 patients. This study explores the association between ALI patterns and the occurrence of long‐term hepatic complications in patients with and without existing chronic liver disease (CLD).
Basile Njei +6 more
wiley +1 more source
Calmodulin and Calcium-release Channels
Biological Research, 2004 Calmodulin (CaM) is a ubiquitous cytosolic protein that plays a critical role in regulating cellular functions by altering the activity of a large number of ion channels.
NAEL NADIF KASRI +4 more
doaj
Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 9, September 2026.Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao +10 more
wiley +1 more source
DHCR24 Alleviates DNA Damage in Senescent Vascular Endothelial Cells via ENKUR/Ca2+ Signaling
Aging Cell, Volume 25, Issue 9, September 2026.In senescent vascular endothelial cells, DHCR24 deficiency triggers ENKUR‐dependent Ca2+ overload, which in turn induces endoplasmic reticulum stress and mitochondrial dysfunction, ultimately exacerbating oxidative stress and DNA damage. ABSTRACT DNA damage is considered one of the major contributors to aging.
Han Li +11 more
wiley +1 more source
Semi-enzymatic synthesis and application of 13C-isotopically labelled inositol-(1,4,5)-trisphosphate
SEMI-ENZYMATIC SYNTHESIS AND APPLICATION OF 13C-ISOTOPICALLY LABELLED INOSITOL-(1,4,5)-TRISPHOSPHATE Semi-enzymatic synthesis and application of 13C-isotopically labelled inositol-(1,4,5)-trisphosphate / Patharkar, Atharva (Rights reserved) (-
Patharkar, Atharva +9 more
core +2 more sources
, 2016 The design of a range of 4-position-modified d-myo-inositol 1,4,5-trisphosphate derivatives is described. The enantioselective synthesis of these compounds is reported, along with initial biological analysis, which indicates that these compounds do not ...
Stuart J. Conway (1280553) +6 more
core +2 more sources
Synthesis of myo-Inositol-1,4,5-trisphosphate and myo-Inositol-1,4-bisphosphate
, 1992 Racemic myo-inositol-1,4,5-trisphosphate and myo-inositol-1,4-bisphosphate, which are respectively a second messenger mobilizing Ca2+ and its physiological metabolite in the intracellular signal transduction pathway, were synthesized from myo-inositol ...
Moon, Sung-Hwan +3 more
core
Studies on ion movements in Malpighian tubules of Locusta migratoria L., with particular reference to their endocrine control [PDF]
, 1990 Intracellular microelectrodes were used in conjunction with ion substitution, agonists and inhibitors of known transport processes and diuretic hormone (DH), to investigate the mechanisms whereby ions cross the basal and apical cell membranes of the ...
Fogg, Kay Elizabeth, Fogg, K.E
core