Results 161 to 170 of about 58,268 (235)

A Comparative Perspective on Functionally-Related, Intracellular Calcium Channels: The Insect Ryanodine and Inositol 1,4,5-Trisphosphate Receptors. [PDF]

Biomolecules, 2021
Toprak U, Doğan C, Hegedus D.
europepmc   +1 more source

Functional investigation of a putative calcium-binding site involved in the inhibition of inositol 1,4,5-trisphosphate receptor activity. [PDF]

J Biol Chem
Arige V, Wagner LE, Malik S, Baker MR, Fan G, Serysheva II, Yule DI.   +6 more
europepmc   +1 more source

Carbenoxolone and 18β-glycyrrhetinic acid inhibit inositol 1,4,5-trisphosphate-mediated endothelial cell calcium signalling and depolarise mitochondria. [PDF]

Br J Pharmacol, 2021
Buckley C, Zhang X, Wilson C, McCarron JG.   +3 more
europepmc   +1 more source

Inositol 1,4,5-Trisphosphate Receptor 1 Gain-of-Function Increases the Risk for Cardiac Arrhythmias in Mice and Humans. [PDF]

Circulation
Sun B, Ni M, Li Y, Song Z, Wang H, Zhu HL, Wei J, Belke D, Cai S, Guo W, Yao J, Tian S, Estillore JP, Wang R, Søndergaard MT, Brohus M, Rohde PD, Mu Y, Vallmitjana A, Benitez R, Hove-Madsen L, Overgaard MT, Fishman GI, Chen J, Sanatani S, Wilde AAM, Fill M, Ramos-Franco J, Nyegaard M, Chen SRW.   +29 more
europepmc   +1 more source

Combined Pharmacophore and Grid-Independent Molecular Descriptors (GRIND) Analysis to Probe 3D Features of Inositol 1,4,5-Trisphosphate Receptor (IP₃R) Inhibitors in Cancer. [PDF]

Int J Mol Sci, 2021
Ismatullah H, Jabeen I.
europepmc   +1 more source

Inositol 1,4,5-Trisphosphate Receptors Regulate Vascular Smooth Muscle Cell Proliferation and Neointima Formation in Mice. [PDF]

J Am Heart Assoc
Huang F, Zhang F, Huang L, Zhu X, Huang C, Li N, Da Q, Huang Y, Yang H, Wang H, Zhao L, Lin Q, Chen Z, Xu J, Liu J, Ren M, Wang Y, Han Z, Ouyang K.   +18 more
europepmc   +1 more source

Inhibition of NPC Intracellular Cholesterol Transporter 1 Dually Regulates Aldosterone Secretion Via the Steroidogenic Acute Regulatory-Related Lipid Transfer Domain-3-Voltage-Dependent Anion Channel 1 Axis and Inositol 1,4,5-Trisphosphate Receptor Type 3-Calcium Signaling. [PDF]

J Am Heart Assoc
Chen J, Chen M, Hu J, Wu Z, Li H, Li W, He F, Peng C, Xu Y, Huang W, Gao R, Li Q, Ma L, Yang S.   +13 more
europepmc   +1 more source

Inositol 1,4,5-Trisphosphate Receptors in Human Disease: A Comprehensive Update. [PDF]

J Clin Med, 2020
Gambardella J, Lombardi A, Morelli MB, Ferrara J, Santulli G.   +4 more
europepmc   +1 more source

Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity. [PDF]

Nat Commun
Márquez-Moñino MÁ, Ortega-García R, Whitfield H, Riley AM, Infantes L, Garrett SW, Shipton ML, Brearley CA, Potter BVL, González B.   +9 more
europepmc   +1 more source

Disease-associated mutations in inositol 1,4,5-trisphosphate receptor subunits impair channel function. [PDF]

J Biol Chem, 2020
Terry LE, Alzayady KJ, Wahl AM, Malik S, Yule DI.   +4 more
europepmc   +1 more source