Results 221 to 230 of about 761,638 (295)

Measuring phytic acid in complex and fermented food matrices: Modified protocol using enzymatic analysis

JSFA reports, Volume 6, Issue 1, Page 4-13, January 2026.
Abstract Background and Objective Quantifying phytic acid in complex or fermented foods is essential for assessing nutritional quality. Conventional enzymatic assays often overestimate phytic acid due to nonspecific hydrolysis of phosphorylated compounds.
Neda Rousta, Mohammad J. Taherzadeh
wiley   +1 more source

Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding.

Nature Chemical Biology, 2011
Huanchen Wang, J. Falck, T. Hall, S. Shears   +3 more
semanticscholar   +1 more source

Wnt Signaling Pathway: Biological Function, Diseases, and Therapeutic Interventions

MedComm, Volume 7, Issue 1, January 2026.
The Wnt signaling pathway is essential for development and tissue homeostasis, while its dysregulation drives diverse diseases. This review systematically outlines its components, functions, regulators, and preclinical models, highlighting secreted frizzled‐related proteins (SFRPs) as context‐dependent, biphasic modulators.
Xiaoyu Jin, Jiahui Wang, Runyi Cao, Dongsheng Jiang   +3 more
wiley   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh, Shubham Mahajan, Sadikalmahdi Abdella, Rehan Khan, Sanjay Garg   +4 more
wiley   +1 more source

Optimizing Peafowl (Pavo cristatus) Fertility and Chick Growth With Mealworm‐Based Feed Supplementation

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Mealworm meal premix supplementation in breeding peafowl diets improved feed conversion, chick growth and early survivability, particularly at higher inclusion levels. The premix supported reproductive performance and chick vitality without adverse effects, indicating its potential as a sustainable functional feed additive.
Sar Zamin Khan, Hanan Al‐Khalaifah, Haris Khan, Rifat Ullah Khan, Shabana Naz, Ala Abudabos, Ibrahim A. Alhidary   +6 more
wiley   +1 more source

Quality Analysis and Detection of Adulterants and Contaminations in Milk/Milk Powder by Raman Spectroscopy

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT Milk and milk powder are central to global nutrition, yet remain vulnerable to adulteration and contamination. Adulteration using water, urea, ammonium sulfate, thiocyanates, detergents, melamine, or compositional changes with whey and carbohydrate fillers undermines nutritional quality, reduces consumer confidence, and challenges regulatory ...
B. Sudarshan Acharya, Sreerag Nair, Abdul Ajees Abdul Salam   +2 more
wiley   +1 more source

Age‐Dependent Metabolomic Signatures of Dietary Restriction in Mice

Aging Cell, Volume 25, Issue 1, January 2026.
Elevated hepatic glutathione (GSH) and 3‐hydroxybutyrate (3‐HB) levels in all ages of mice demonstrate an enhanced protection against oxidative stress and improvement in energy metabolism during chronic dietary restriction (DR). However, high protein or muscle degradation in liver of young mice, and large accumulation of hepatic glycogen and excessive ...
Ji‐sue Lee, Vindya H. J. Hetti Arachchige, Eun‐Hee Kim, Eunjung Bang, Young‐Shick Hong   +4 more
wiley   +1 more source

The Selective Bromodomain and Extra‐Terminal Domain (BET) Inhibitor RVX‐208 Reduces Cocaine‐Seeking Behaviour and Alters Proteomic Pathways in the Nucleus Accumbens

Addiction Biology, Volume 31, Issue 1, January 2026.
Rats treated with the domain‐selective BET inhibitor RVX‐208 during a 2‐week forced abstinence period exhibited a reduction in cocaine‐seeking behaviour but not sucrose seeking or open field behaviour. This treatment effect was associated with proteomic changes in pathways relevant to dopaminergic and glutamatergic signalling in the nucleus accumbens ...
Tyler J. Sacko, Afshin Seyednejad, Jesse Engelhardt, Gregory C. Sartor   +3 more
wiley   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, Volume 36, Issue 1, January 2026.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Comparative metabolomic and transcriptomic analysis of 2D and 3D mesenchymal stem cell cultures for improved therapeutic applications

British Journal of Pharmacology, Volume 183, Issue 2, Page 379-392, January 2026.
Comparative metabolomic and transcriptomic profiling reveals distinct metabolic shifts and reduced proliferation in 3D MSC spheroids, providing insights to optimise MSC‐based therapies. Abstract Background and Purpose Mesenchymal stem cells (MSCs) are used widely in regenerative medicine due to their multipotency and immunomodulatory properties ...
Manju Shrestha, Yun‐Seo Kil, Yunju Jo, Simmyung Yook, Ki Hyun Kim, Dongryeol Ryu, Joo‐Won Nam, Jee‐Heon Jeong   +7 more
wiley   +1 more source