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A Discrete Signaling Function for an Inositol Pyrophosphate

Science's STKE, 2007
Inositol pyrophosphates were, until recently, without clearly defined functions. Two recent papers in Science have now clearly defined a function for an IP 7 pyrophosphate (inositol hexaphosphate with one pyrophosphate) that is the product of the enzyme encoded by the Vip1
openaire   +2 more sources

Understanding the biological significance of diphosphoinositol polyphosphates (‘inositol pyrophosphates’)

Biochemical Society Symposia, 2007
Among the many derivatives of the inositol-based signalling family are a subgroup that possess diphosphates. In this review, some recent research into the actions of these specialized polyphosphates is analysed, and key goals for future studies are identified, which, it is hoped, will result in the wider cell-signalling community giving considerably ...
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Inositol pyrophosphate kinases in health and disease

FEBS Letters
Inositol phosphates (InsPs) are intracellular signaling molecules that are essential for life. Inositol pyrophosphates, a subset of inositol phosphates, are the end products of inositol phosphate metabolism. In mammalian cells, up to 90% of inositol pyrophosphates are 5‐diphosphoinositol 1,2,3,4,6‐pentakisphosphate (5PP‐InsP
Changchang Xing   +6 more
openaire   +1 more source

Signals | The Inositol Pyrophosphate Signaling Family

2021
Soumyadip Sahu, Stephen B. Shears
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Inositol derivatives: evolution and functions

Nature Reviews Molecular Cell Biology, 2008
Robert Hall Michell
exaly  

Structure of HDAC3 bound to co-repressor and inositol tetraphosphate

Nature, 2012
Louise Fairall   +2 more
exaly  

Inositol phosphates are assembly co-factors for HIV-1

Nature, 2018
Robert A Dick   +2 more
exaly  

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