Results 91 to 100 of about 2,441,106 (300)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The Effect of Applying Argument Driven Inquiry Models to the Critical Thinking Skills of Students Based on Gender Differences

Scientiae Educatia: Jurnal Pendidikan Sains, 2019
This study aims to determine the effect of the application of the Argument-Driven Inquiry (ADI) learning model on students' critical thinking abilities and to determine the differences in critical thinking skills between female and male students in the ...
Laya Nazila, Undang Rosidin, I Wayan Distrik, Kartini Herlina, Neni Hasnunidah   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Enhancing Inquiry-Based Learning Environments with the Power of Problem-Based Learning to Teach 21st Century Learning and Skills

, 2015
This chapter provides an outline of how the essential elements of Problem-based Learning (PBL) can be adapted to enhance inquiry-based learning environments and in the process teach 21st century skills. It uses a case study of a first year nursing course
Megan Y. C. A. Kek, Kek, Megan Y. C. A., Huijser, Henk, Ruth Terwijn, Terwijn, Ruth, Henk Huijser   +5 more
core   +1 more source

Employee demand for skills: evidence and policy review : UK Commission for Employment and Skills Research Report no. 3 [PDF]

, 2009
This report presents the results of a detailed review of evidence and policy relating to the factors that influence the engagement of the individual in skills development.
Dutton, Matthew, Lindsay, Colin, Johnson, Steve, Pearson, Claire, McQuaid, Ronald, Sawicki, Szymon   +5 more
core   +3 more sources

Desirable difficulties during the development of active inquiry skills

Cognition, 2017
This study explores developmental changes in the ability to ask informative questions, hypothesizing a link between the ability to update beliefs in light of evidence and the ability to ask informative questions. Five- to ten-year-old children played an iPad game asking them to identify a hidden insect.
Kachergis, George, Rhodes, Marjorie, Gureckis, Todd   +2 more
openaire   +4 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Inquiry Game: Assessing Inquiry Skills in Low-Income Preschoolers

, 2001
Inquiry skills in young low-income children may be an important point of intervention for promoting school readiness and later academic achievement. The current study aimed to investigate and measure the inquiry skills of low-income preschoolers.
Nayfeld, Irene
core   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

THE EFFECTS OF GENDER AND TYPE OF INQUIRY CURRICULUM ON SIXTH GRADE STUDENTS’ SCIENCE PROCESS SKILLS AND EPISTEMOLOGICAL BELIEFS IN SCIENCE

, 2014
The purpose of this study was to investigate the impact of gender and type of inquiry curriculum (open or structured) on science process skills and epistemological beliefs in science of sixth grade students.
Zaleta, Kristy
core