Results 71 to 80 of about 746,711 (260)

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

open access: yesAdvanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou   +9 more
wiley   +1 more source

The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics

open access: yesAdvanced Science, EarlyView.
Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye   +5 more
wiley   +1 more source

Allergenic potential of insect proteins: cross-reactivity, detection, degradation, and implications for food safety and labelling

open access: yesFood Science of Animal Products
The growing global demand for protein, driven by population expansion, has highlighted the need for sustainable and nutritionally rich alternatives. Insect protein presents a promising solution, offering a high-quality, environmentally sustainable source
Dongdong Ni
doaj   +1 more source

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

open access: yesAdvanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li   +7 more
wiley   +1 more source

A High‐Quality Reference Genome and Comparative Genomics of the Widely Farmed Banded Cricket (Gryllodes sigillatus) Identifies Selective Breeding Targets

open access: yesEcology and Evolution
Farmed insects have gained attention as an alternative, sustainable source of protein with a lower carbon footprint than traditional livestock. We present a high‐quality reference genome for one of the most commonly farmed insects, the banded cricket ...
Shangzhe Zhang   +7 more
doaj   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

open access: yesAdvanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun   +5 more
wiley   +1 more source

Black soldier fly larvae (Hermetia illucens) frass and sheddings as a compost ingredient

open access: yesFrontiers in Sustainable Food Systems
One of the byproducts from rearing Black soldier fly larvae (BSFL) is its excrement, referred to as frass, and sheddings. As the commercial insect rearing industry is emerging in the U.S., there is not yet an established market for frass although the ...
Beatrice Jasso   +3 more
doaj   +1 more source

Species-Specific Discrimination of Insect Meals for Aquafeeds by Direct Comparison of Tandem Mass Spectra

open access: yesAnimals, 2019
Insect protein has the potential to become a sustainable feed ingredient for the rapidly growing aquaculture industry. In the European Union, insect derived protein is placed under the same legislation as processed animal proteins (PAP).
Ikram Belghit   +8 more
doaj   +1 more source

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

open access: yesAdvanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu   +12 more
wiley   +1 more source

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