Results 241 to 250 of about 4,048,456 (298)

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Purcell‐Enhanced Spectrally Precise Emission in Dual‐Microcavity Organic Light‐Emitting Diodes

Advanced Functional Materials, EarlyView.
Spectrally precise emission from broadband organic light‐emitting diodes is realized via a dual‐microcavity strategy. This architecture achieves narrowband emission (full width at half maximum, FWHM = 21 nm) with ultrapure color approaching BT.2020 by enhancing the Purcell effect via coupling of excitons with dual‐microcavity resonance.
Jun Yong Kim, Sang Youn Lee, Kwan Hyun Cho, Yun Seon Do   +3 more
wiley   +1 more source

Smarter Sensors Through Machine Learning: Historical Insights and Emerging Trends across Sensor Technologies

Advanced Functional Materials, EarlyView.
This review highlights how machine learning (ML) algorithms are employed to enhance sensor performance, focusing on gas and physical sensors such as haptic and strain devices. By addressing current bottlenecks and enabling simultaneous improvement of multiple metrics, these approaches pave the way toward next‐generation, real‐world sensor applications.
Kichul Lee, Osman Gul, Yeongjae Kwon, Jaeseok Jeong, Seokjoo Cho, Jihyeon Ahn, Jehee Yu, Cheolmin Kim, Donho Lee, Hyeonseok Han, Byeongju Lee, Jungrak Choi, Ji‐Hwan Ha, Yongrok Jeong, Kyungnam Kang, Ali Javey, Junseong Ahn, Inkyu Park   +17 more
wiley   +1 more source

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Bacterial Insertion Sequences

1996
While DNA has a property of being fundamentally stable as invariable genetic information, studies on gene expression and gene organization have revealed that the genome is often subject to dynamic changes. Some of these changes are brought about by mobile genetic elements which have been found in prokaryotic and eukaryotic genomes so far studied ...
F, Ohtsubo, Y, Sekine
openaire   +2 more sources

Structural analysis of insertion sequence IS5

Nature, 1982
Among the transposable DNA elements that have been detected in bacterial genomes and plasmids1–3, the small insertion sequence (IS) elements have been recognized as a class of autonomous, basic units of transposition. IS elements are not only fully competent of transposition and able to cause several other related chromosomal aberrations such as ...
M, Kröger, G, Hobom
openaire   +2 more sources

Insertion sequence elements in Lactococcus garvieae

Gene, 2015
Insertion sequences are the simplest intracellular Mobile Genetic Elements which can occur in very high numbers in prokaryotic genomes, where they play an important evolutionary role by promoting genome plasticity. As such, the studies on the diversity and distribution of insertion sequences in genomes not yet investigated can contribute to improve the
G. Eraclio, G. Ricci, M.G. Fortina
openaire   +2 more sources

IS200: A salmonella-specific insertion sequence

Cell, 1983
A new IS element (IS200) has been identified in Salmonella. The sequence was identified as an IS element by the following criteria: its insertion caused the mutation hisD984; six copies of the sequence are present in strain LT2 of S. typhimurium; and transposition of the sequence has been observed on several occasions.
S, Lam, J R, Roth
openaire   +2 more sources

Insertion Sequence Duplication in Transpositional Recombination

Science, 1983
Insertion sequences (IS) are discrete segments of DNA that can transpose from one genomic site to another and promote genetic rearrangements. A question that is central to understanding the mechanism of transpositional recombination is whether genetic rearrangements are accompanied by duplication of the IS that promotes them.
T A, Weinert, N A, Schaus, N D, Grindley
openaire   +2 more sources

The Staphylococcal Insertion Sequence IS257Is Active

Plasmid, 1995
The plasmid pJ3356 confers high-level mupirocin resistance on a strain of Staphylococcus aureus isolated from a hospital. The plasmid also carries two copies of IS257. Recombination of an IS257-containing plasmid conferring erythromycin resistance, pOX7-IS, into either of the IS257s of pJ3356 has been observed.
C, Needham, W C, Noble, K G, Dyke
openaire   +2 more sources

Insertion Sequences and Transposons

2014
Transposable elements (TEs) have been defined as DNA sequences able to insert at many sites in the genome. At present there are about 500 TEs identified in many different bacterial species. Most insertion sequence (IS) elements and transposons were discovered after their transposition into genes of interest.
Ronald Chalmers, Michel Blot
openaire   +1 more source