Results 71 to 80 of about 2,746,237 (260)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Unanchored simulated treatment comparison on survival outcomes using parametric and Royston-Parmar models with application to lenvatinib plus pembrolizumab in renal cell carcinoma

open access: yesBMC Medical Research Methodology
Background Population-adjusted indirect comparison using parametric Simulated Treatment Comparison (STC) has had limited application to survival outcomes in unanchored settings.
Christopher G. Fawsitt   +4 more
doaj   +1 more source

Dir. Orson Welles's Citizen Kane

open access: yes, 2023
Insight Text Guides take students into the deeper layers of meaning in a range of popular novels, plays, films, short-story collections and nonfiction texts. They are designed to develop detailed knowledge, in-depth understanding and genuine insight into
Barnes, Diana
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

RAG4DS: Retrieval-Augmented Generation for Data Spaces—A Unified Lifecycle, Challenges, and Opportunities

open access: yesIEEE Access
Retrieval-Augmented Generation (RAG) has gained significant attention from many researchers as an effective solution to address the hallucination issue of Foundational Models (FMs), particularly Large Language Models (LLMs). Although the RAG framework is
Majjed Al-Qatf   +7 more
doaj   +1 more source

Jon Krakauer's Into Thin Air

open access: yes, 2023
Insight Text Guides take students into the deeper layers of meaning in a range of popular novels, plays, films, short-story collections and nonfiction texts. They are designed to develop detailed knowledge, in-depth understanding and genuine insight into
Barnes, Diana
core  

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Smallholders download and share videos from the Internet to learn about sustainable agriculture

open access: yesInternational Journal of Agricultural Sustainability, 2019
Of 1,211 farmers and their representatives registered on www.accessagriculture.org, 142 participated in an on-line survey in November 2017, designed to learn farmer’s opinions of Access Agriculture, an NGO which hosts a digital platform where anyone can ...
Jeffery W. Bentley   +4 more
doaj   +1 more source

Research, Analysis and Insight into National Standards (RAINS) Project Final Report: National Standards and the Damage Done [PDF]

open access: yes, 2013
This is the final report of the Research Analysis and Insight into National Standards (RAINS) project, a three-year study of the enactment of the National Standards policy in six diverse primary and intermediate schools.
Thrupp, Martin, White, Michelle
core  

Charmaine Papertalk Green & John Kinsella's False Claims of Colonial Thieves

open access: yes, 2023
Insight Text Guides take students into the deeper layers of meaning in a range of popular novels, plays, films, short-story collections and nonfiction texts. They are designed to develop detailed knowledge, in-depth understanding and genuine insight into
Barnes, Diana
core  

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