Results 71 to 80 of about 8,338,005 (303)

Loss of FKBP5 Affects Neuron Synaptic Plasticity: An Electrophysiology Insight [PDF]

open access: yes, 2019
FKBP5 (FKBP51) is a glucocorticoid receptor (GR) binding protein, which acts as a co-chaperone of heat shock protein 90 (HSP90) and negatively regulates GR.
Deng, Ran   +14 more
core   +1 more source

Insight solutions are correct more often than analytic solutions

open access: yesThinking and Reasoning, 2016
How accurate are insights compared to analytical solutions? In four experiments, we investigated how participants' solving strategies influenced their solution accuracies across different types of problems, including one that was linguistic, one that was
C. Salvi   +4 more
semanticscholar   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

InSight Aerothermal Environment Assessment [PDF]

open access: yes
The Mars Interior Exploration using Seismic Investigations, Geodesy and Heat Transport (InSight) spacecraft, which successfully touched down on the planet surface on November 26, 2018, was proposed as a near build-to-print copy of the Mars Phoenix ...
Beck, Robin A. S.   +5 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Scholarly insight Spring 2018: a Data wrangler perspective [PDF]

open access: yes, 2018
In the movie classic Back to the Future a young Michael J. Fox is able to explore the past by a time machine developed by the slightly bizarre but exquisite Dr Brown.
Calder, Kathleen   +14 more
core  

Insight into nanoparticle cellular uptake and intracellular targeting

open access: yesJournal of Controlled Release, 2014
Collaborative efforts from the fields of biology, materials science, and engineering are leading to exciting progress in the development of nanomedicines.
Basit Yameen   +5 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

VIRTUOUS INSIGHTFULNESS [PDF]

open access: yesEpisteme, 2016
AbstractInsight often strikes us blind; when we aren't expecting it, we suddenly see a connection that previously eluded us – a kind of Aha! experience. People with a propensity to such experiences are regarded as insightful, and insightfulness is a paradigmatic intellectual virtue. What's not clear, however, is just what it is in virtue of which being
openaire   +1 more source

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