Results 61 to 70 of about 904,380 (360)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Geophysical Research LettersA new high‐spatial resolution camera on the International Space Station used OH nightglow in the H‐band to image the ground at an ∼70 m pixel footprint over an ∼280 km swath and maintained this resolution during its 1.5 s exposure.
J. H. Hecht +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A habitus of instability: youth homelessness and instability
Journal of Youth Studies, 2015 This research introduces the concept of a habitus of insecurity to account for the lives of homeless young people. It outlines how conditions of existence are internalised and how homeless young people come to expect and in turn recreate instability in their lives.
openaire +3 more sources
Controlling contractile instabilities in the actomyosin cortex
eLife, 2017 The actomyosin cell cortex is an active contractile material for driving cell- and tissue morphogenesis. The cortex has a tendency to form a pattern of myosin foci, which is a signature of potentially unstable behavior. How a system that is prone to such
M. Nishikawa +3 more
semanticscholar +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Acoustic and Large Eddy Simulation studies of azimuthal modes in annular combustion chambers [PDF]
, 2012 The objectives of this paper are the description of azimuthal instability modes found in annular combus- tion chambers using two numerical tools: (1) Large Eddy Simulation (LES) methods and (2) acoustic solv- ers.
Wolf, Pierre +4 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Frontiers in Astronomy and Space Sciences, 2022 An Extreme Ultraviolet (EUV) jet that occurred around 22:30 on July 2, 2012 was observed by the Atmospheric Imaging Assembly (AIA) on-board the Solar Dynamics Observatory (SDO). There were two phases of the jet. In Phase 1, two blobs were observed.
Jie Chen +11 more
doaj +1 more source