Results 101 to 110 of about 2,390,832 (281)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
, 2009 Local lattice structures of La$_{1.85}$Sr$_{0.15}$Cu$_{1-x}$M$_x$O$_4$ (M=Mn, Ni, and Co) single crystals are investigated by polarized extended x-ray absorption fine structure (EXAFS).
Oyanagi, H., Zhang, C. J.
core +1 more source
Problems of Atomic Science and Technology, 2019 The dynamics of the oscillator system is investigated. The conditions under which this dynamics becomes unstable are determined. In particular, it is shown that plasma in constant magnetic field becomes unstable if its density exceeds a certain critical value. In this case, instability develope (oscillatory instability).
openaire +2 more sources
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Growth, Volatility & Political Instability: Non Linear Time Series Evidence for Argentina 1896-2000 [PDF]
, 2007 What is the relationship between economic growth and its volatility? Does political instability affect growth directly or indirectly, through volatility?
Campos, Nauro F., Karanasos, Menelaos
core
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Experimental Investigation of Flow Domain Division in Beds Packed with Different Sized Particles
Energies, 2017 Seepage in a medium packed with particles of variable granular size can be seen in many fields of engineering applications. Due to the relative complex spatial aspect of pore geometry, there are notable differences in the critical parameters of flow ...
Xin Yang +3 more
doaj +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
Shear instability of an axisymmetric air-water coaxial jet
, 2018 We study the destabilization of a round liquid jet by a fast annular gas stream. We measure the frequency of the shear instability waves for several geometries and air/water velocities.
Cartellier, Alain +2 more
core +3 more sources