Results 51 to 60 of about 49,482,926 (251)

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham   +7 more
wiley   +1 more source

On the road to Enlighten-ment: establishing an institutional repository service for the University of Glasgow [PDF]

open access: yes, 2007
Purpose – The purpose of this paper is to chart the development and growth of open access and institutional repositories at the University of Glasgow, Scotland from initial work in 2001 to the University's recently launched service, Enlighten.
Nixon, William J., Greig, Morag
core   +1 more source

INSTITUTIONAL REPOSITORY: EMPLOYMENT IN EDUCATION

open access: yesІнформаційні технології і засоби навчання, 2012
The article investigated the concept of «institutional repository» and determined the aspects of institutional repositories in higher education.
Vasyl P. Oleksyuk, Olesya R. Oleksyuk
doaj  

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

open access: yesAdvanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena   +3 more
wiley   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

open access: yesAdvanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren   +6 more
wiley   +1 more source

DSpace 跨機構虛擬儲存庫之可行性研究 The Feasibility Study of DSpace towards a Virtual Cross-Institutional Repository [PDF]

open access: yesJiàoyù zīliào yǔ túshūguǎn xué, 2004
DSpace已被學術機構廣泛使用,以達到資訊之管理與再利用的工具軟體。本文選擇數位典藏國家型科技計畫後設資料工作組(Metadata Architecture and Application Team, MAAT)網站為研究案例,來檢驗 DSpace系統是否適用於跨組織虛擬數位典藏庫的可行性議題。MAAT網站是一個靜態網站,其中包含全台灣各個機構不同的數位圖書館計畫所產生的大量文件。本研究歸納出,若DSpace的某些功能能提供更有彈性的客製化,例如Community與Collection的階層架構與查詢,
Ya-Ning Chen   +2 more
doaj  

Autonomous Reconfigurable Modular Conductive Hydrogels for Adaptive and Degradable Bioelectronic Interfaces

open access: yesAdvanced Materials Technologies, EarlyView.
Bridging rigid electrodes with soft, irregular tissues demands more than conductivity alone. Modular conductive hydrogels autonomously reconfigure into conformal electrode‐tissue interfaces, coupling mixed ionic‐electronic conduction with tissue‐like mechanics, self‐healing, and degradability.
Matthew K. Burgess   +4 more
wiley   +1 more source

Perpetual Beta: Assessing the Institutional Repository [PDF]

open access: yes, 2013
The institutional repository (IR) is more than an end product that holds content. It is a complex system with a variety of participants and a development course that can most accurately be described as “perpetual beta.” As a software system with both ...
Sivak, Allison, Vanderjagt, Leah
core   +1 more source

The institutional repository in the digital library [PDF]

open access: yes, 2011
Chapter 1We begin by looking at the concept of institutional repositories within the broader context of digital libraries. ‘Digital libraries’ can mean many things, but we consider them to be libraries first and foremost, and built upon the enduring ...
MacColl, John   +2 more
core   +2 more sources

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