Results 51 to 60 of about 872,727 (291)

Harvesting Knowledge [PDF]

open access: yes, 2010
{Excerpt} If 80% of knowledge is unwritten and largely unspoken, we first need to elicit that before we can articulate, share, and make wider use of it.
Serrat, Olivier
core   +1 more source

Towards a Re-Definition of Government Interpreters' Agency Against a Backdrop of Sociopolitical and Cultural Evolution: A Case of Premier's Press Conferences in China [PDF]

open access: yes, 2018
The sociopolitical and cultural evolution as a result of the Reform and Opening up in 1978, facilitated not least by the inexorable juggernaut of globalization and technological advancement, has revolutionized the way China engages domestically and ...
Ahmad, Norhafizan   +3 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Metaphorical Framing in Political Translation: Translating Xi Jinping’s Ecological Progress

open access: yestransLogos: Translation Studies Journal
Metaphors are intricate linguistic devices and potent cognitive-discursive tools for persuasion in both source texts (ST) and target texts (TT). They primarily function in framing, namely the selection and clarification of cognitive domains, a ...
Enci HUANG, Qijun SONG
doaj   +1 more source

Translation at the United Nations as Specialized Translation

open access: yesJoSTrans: The Journal of Specialised Translation, 2008
Multilingualism is one of the foundations of the United Nations (UN) and  translation of UN documents plays an important political and practical role in the functioning of the Organ isation. This paper argues that UN translation is a special ised area of
Deborah Cao Xingmin Zhao
doaj   +1 more source

Translation and response between Maurice Blanchot and Lydia Davis [PDF]

open access: yes, 2011
When an author translates a text by another writer, this translation is one form of a response to that text. Other responses may appear in their own writings that are more inflected with their authorial persona.
Evans, Jonathan
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Understanding digital eco-innovation in municipalities: An institutional perspective [PDF]

open access: yes, 2015
Municipalities consume over 67% of global energy and are responsible for over 70% of greenhouse gas emissions (GHG). The Intergovernmental Panel on Climate Change warns that rapid adjustments need to happen at a global level, or the effects of climate ...
Butler, T, Hackney, RA
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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