Results 131 to 140 of about 5,881,292 (359)

Understanding Institutions: A Multi-Dimensional Approach [PDF]

, 2018
With the rise of nativist policies throughout the world, the growing dangers posed by climate change and rising income inequality, and ever-increasing threats to the rule of law, many turn to the institutions of democracy to achieve desired policy goals.
Brescia, Raymond H.
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Preferential cyclooxygenase inhibition by Jasminum sambac: A possible relationship with potent anti-arthritic activity

Journal of Traditional and Complementary Medicine, 2021
Vipin Dhote, Uma Dangi, Avinash Singh Mandloi, Maneesh Soni, Durgesh Nandan Shukla, Manisha Kawadkar, Aditya Ganeshpurkar   +6 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Sarcomatoid areas of urothelial carcinoma are enriched for CD163‐positive antigen‐presenting cells

The Journal of Pathology: Clinical Research
Sarcomatoid urothelial carcinoma (SUC) is a rare histologic subtype with poor prognosis. While there is known intra‐tumoral heterogeneity between individual SUC tumors, the relationship between sarcomatoid and conventional urothelial carcinoma (CUC ...
Burles A Johnson III, Vamsi Parimi, Sonia Kamanda, David C Corney, Woonyoung Choi, Jean Hoffman‐Censits, Max Kates, David J McConkey, Noah M Hahn, Andres Matoso   +9 more
doaj   +1 more source

American Hydroids, Part I, The Plumularidæ . By C. C. Nutting. Washington, 1900. Published by the Smithsonian Institution. Pp. 285; pls. 34. [PDF]

, 1900
T. D. A. Cockerell
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Is the use of the investment resources allocated to municipalities in Cameroon efficient?

Public Sector Economics
The aim of this study is to assess the technical efficiency of the use of investment resources allocated to municipalities in Cameroon. The data used come from the Special Inter-municipal Equipment and Intervention Fund (FEICOM), the National ...
Sylvain Ngô Ndjang, Saturnin Bertrand Nguenda Anya, Fabrice Nzepang   +2 more
doaj   +1 more source

Wind waves and swell : principles in forecasting / prepared for the Hydrographic Office, U.S. Navy, by the Scripps Institution of Oceanography.

, 1940

openalex   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source