Results 71 to 80 of about 4,628,960 (295)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 2011 This course underlines the processes for designing effective and efficient instruction. The course introduces phases of Instructional Design. The course provides necessary knowledge, skills in identify instructional goals, conduct instructional analysis,
Çağıltay, Kürşat
core
Frontiers in EducationTeachers constantly need to make decisions about which instructional strategies to apply in their classrooms, in particular in the context of so-called adaptive teaching.
Doris Neubauer-Hametner +3 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Organizational Learning and Instructional Technology Review Team Report 2009
, 2010 Academic Program Review - Organizational Learning and Instructional Technology - Review Team Report 2009Organizational Learning and Instructional Technology (OLIT) Review Team Report ...
Organizational Learning and Instructional Technology, 2009
core
Curriculum Considerations for Developing Mathematical Talent in Elementary Students
Education SciencesTo effectively nurture the talents of elementary students with mathematical talent they need to be challenged with an advanced curriculum that is designed with their specific needs in mind.
M. Katherine Gavin
doaj +1 more source
ONLINE INSTRUCTIONAL STRATEGIES
EPRA International Journal of Multidisciplinary Research (IJMR), 2022 Online instructional strategies refer to the methods and approaches that guide the organization of learning activities, course content, and student engagement in online courses. Strategies frequently adopted in online courses include (1) promoting interactivity through asynchronous and synchronous communication or delivery (2) facilitating the ...
openaire +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
International Journal of Studies in PsychologyThis paper discusses instructional design considerations for secondary school students' learning physics concepts, framed through cognitive development theories, particularly Jean Piaget's stages.
Adeniyi Michael Adeduyigbe +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source