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This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Announcement, Instructional Design Strategies Instructional Materials Training, October 16, 2014
Announcement for a training on designing instructional materials for ...
University of South Florida St. Petersburg. Nelson Poynter Memorial Library. Online Learning and Instructional Technology Services +1 more
core
The nature and quality of the mathematical connections teachers make
Current reforms in mathematics education emphasise the need for pedagogy because it offers learners opportunities to develop their proficiency with complex high-level cognitive processes.
Michael K. Mhlolo +2 more
doaj +1 more source
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Digital divide and teaching modality: It's role in technology and instructional strategies. [PDF]
Kormos E, Wisdom K.
europepmc +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Educational experts advocate for storytelling’s community building aspects; it is also a valuable tool for deepening students’ cognitive engagement.
Corrie Whitmore, Kathryn Schild
doaj
Comparing instructional strategies to support student teachers' learning to prepare an open-minded citizenship education lesson. [PDF]
van Brussel S +3 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Instructional Strategies In Math
Marginalized students face a range of gaps in experience, highlighting the importance of better understanding these students’ opportunities to learn.
Kelley Durkin +2 more
core +1 more source

