Results 51 to 60 of about 3,475,630 (306)

Investigating instructional strategies for using social media in formal and informal learning

International Review of Research in Open and Distributed Learning, 2012
Despite the high popularity of personal use of online social media, a low percentage of students and instructors use them for educational purposes.
Baiyun Chen, Thomas Bryer
doaj   +3 more sources

A Disarray Around the Theme of Lesson Planning: Definition and Characterization of its Constituent Elements

Revista Brasileira de Pesquisa em Educação em Ciências, 2020
This paper aims to investigate the different meanings that the constituent elements of lesson planning have assumed in the works of Science Education and proposes, from a critical approach, the delimitation of its essential constituent elements, as well ...
Milena Alves, Amadeu Moura Bego
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Research Notes ~ Instructional Strategies in Teaching Engineering at a Distance: Faculty perspective

International Review of Research in Open and Distributed Learning, 2008
This paper presents research on a convenience sample of the Open University of Sri Lanka’s engineering faculty. Examined in this research are faculty’s opinions on the instructional strategies they use to teach engineering courses at a distance.
S. Anbahan Ariadurai, Rajalingam Manohanthan   +1 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Enhancing English speaking skills through screencast feedback: a technique explored with Spanish-speaking undergraduates

Cogent Education
For non-native speakers, speaking effectively in English is a relevant skill necessary for academic and professional success, with oral communication abilities often determining one’s capacity to present ideas and engage in meaningful conversations ...
Yéssica Aguilera-Fuentes, Mabel Ortiz-Navarrete   +1 more
doaj   +1 more source

Team-based learning versus interactive lecture in achieving learning outcomes and improving clinical reasoning skills: a randomized crossover study

BMC Medical Education, 2022
Background This study aimed to investigate the impact of interactive lecture (IL) and team-based learning (TBL) on improving clinical reasoning skills (CRSs) and achieving learning outcomes (LO).
Muhammad Imran, Taher Fawzy Halawa, Mukhtiar Baig, Ahmed Mohammed Almanjoumi, Mohammed Mustafa Badri, Waleed Ahmed Alghamdi   +5 more
doaj   +1 more source

National E-Waste Management Strategy 2019-2024 [PDF]

, 2019
The National E-waste Management Strategy is a five-year plan covering the period 2019/20 to 2023/24. The E-waste Strategy has five thematic areas aimed at resource mobilization for proper E-waste management, raising awareness, strengthening Kenya’s E ...

core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source