Results 71 to 80 of about 3,475,630 (306)

Siaya County Youth Agribusiness Strategy 2022-2027

, 2022
This strategy aims at increasing agricultural productivity of select high value enterprises through promoting a value chain development approach which will provide opportunity for employability or entrepreneurship among the youth. The objectives of the

core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Strategies for instructional computing [PDF]

Behavior Research Methods & Instrumentation, 1983
Instructional computing in psychology has become increasingly important to undergraduate and graduate curricula. Four modes of instructional computing, drill and practice, data generators, experiment simulators, and gaming, are described and illustrated with actual programs.
openaire   +1 more source

National Tourism Strategy 2013-2018 [PDF]

, 2013
This National Tourism Strategy is a culmination of extensive stakeholder involvement and participation. It is also a fulfillment of the Tourism Act 2011, Section 3.

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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

FOSTERING DEEP LEARNING APPROACH WITH SMALL GROUP DISCUSSION (SGD

Pakistan Armed Forces Medical Journal, 2018
Objective: To demonstrate the effect of SGD Small Group discussion in fostering deep learning in final Year MBBS students. Study Design: A Quasi experimental design, single arm study (quantitative method).
Qazi Masroor Ali, Syed Hashim Raza, Sadia Masroor   +2 more
doaj  

Effects of Gagné's instructional model on performance and retention in Algebra among secondary school students in Nigeria

Frontiers in Education
BackgroundAlgebra remains a challenging aspect of the secondary school mathematics curriculum in Nigeria, contributing to persistent learning difficulties and poor achievement.ObjectivesThis study examined the effect of Gagné's instructional strategy on ...
Effiom William Anietimfon, Yusuf Feyisara Zakariya, Yusuf Feyisara Zakariya, Ibrahim Omeiza Idris, Muhammed Kabir Falalu   +4 more
doaj   +1 more source

Science Fiction as an Instructional Strategy: Foundations, Procedures, and Results for Pre-service Teachers. [PDF]

Int J Sci Math Educ, 2023
Ağlarcı Özdemir O, Önen Öztürk F.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source