Results 211 to 220 of about 4,021,411 (294)

Perspectives of Older Adults and Their Caregivers on Post-Discharge Medication Management: A Qualitative Study. [PDF]

Health Sci Rep
Wood BS, Buse C, Niznik JD, Mournighan KJ, Davis JR, Lynch DH.   +5 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Survey on the Actual Use of Topical Anti-Inflammatory Drugs Among Patients with Atopic Dermatitis. [PDF]

Dermatol Ther (Heidelb)
Murota H, Noto S, Matsukawa M, Konishi Y, Michikami D, Toda R, Nakahara T.   +6 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Evaluating Spanish Translations of Emergency Department Discharge Instructions by a Large Language Model: Tool Validation and Reliability Study. [PDF]

JMIR Form Res
Carreras Tartak JA, Brewster RC, Arango Isaza D, Berumen Martinez A, Grafals A, Adusumilli P, Fitzgerald T, Orcutt R, Nathanson LA, Haimovich AD.   +9 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Fluid and crystallized cognitive abilities differentially predict successful regulation of positive versus negative emotion. [PDF]

Emotion
Growney CM, Balota DA, English T.
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Use of an AI-Based Tool (Human Experiences and Reflections Data Connector) to Improve Discovery and Reuse of Archived Qualitative Data: Protocol for an Algorithm Development and Validation Study.

JMIR Res Protoc
Leonard T, Stimpson JP, Cano MÁ, Shi W, Abaragu A, Zhang S.   +5 more
europepmc   +1 more source

Implicit association tests for all: Using iatgen for non-English and offline samples. [PDF]

PLoS One
Santos JO, Do Bú E, Hara T, Mendonça C, Hagá S, Pogacar R, Kouril M.   +6 more
europepmc   +1 more source