A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Correction: Jonsdotter et al. MerTK and the Role of Phagoptosis in Neonatal Hypoxia-Ischemia. <i>Cells</i> 2025, <i>14</i>, 1862. [PDF]
Jonsdotter A +6 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Vertex: A Semantic Graph-Based Indoor Navigation System with Vision-Language Landmark Verification. [PDF]
Ferri-Molla I +4 more
europepmc +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Legal Decision Biases in GPT: A Comparison with Human Judgment. [PDF]
Bessis TF +4 more
europepmc +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Challenges faced by adolescents and lung function technicians in Anuradhapura district, Sri Lanka, during spirometry: a qualitative study. [PDF]
Perera D +5 more
europepmc +1 more source
Feasibility and acceptability of COVID-19 self-testing offered through community screening posts in Mozambique: a mixed-methods study. [PDF]
Issufo S +18 more
europepmc +1 more source
Patient Education Deficits and Medication Knowledge Gaps Among Post-Percutaneous Coronary Intervention Patients: A Cross-Sectional Study of Communication Quality and Adherence in Saudi Cardiac Care. [PDF]
Aljuhani M +3 more
europepmc +1 more source

