Results 51 to 60 of about 1,971,504 (262)

Instruction Following without Instruction Tuning

CoRR
Instruction tuning commonly means finetuning a language model on instruction-response pairs. We discover two forms of adaptation (tuning) that are deficient compared to instruction tuning, yet still yield instruction following; we call this implicit instruction tuning.
John Hewitt, Nelson F. Liu, Percy Liang, Christopher D. Manning   +3 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Learning to Instruct for Visual Instruction Tuning

CoRR
NeurIPS ...
Zhihan Zhou 0002, Feng Hong 0004, Jiaan Luo, Jiangchao Yao, Dongsheng Li, Bo Han 0003, Ya Zhang 0002, Yanfeng Wang 0001   +7 more
openaire   +2 more sources

FUNCTION OF FEEDBACK AND INSTRUCTIONS PRESENCE OR ABSENCE IN DESCRIPTION ELABORATION ON CONDITIONAL DISCRIMINATION TASKS [PDF]

Acta Colombiana de Psicología, 2007
The function of rules and instructions to facilitate, maintain or modify the behaviour of individuals has been widely explored in a great variety of tasks.
Guerrero Radillo, Alejandra Paola, Ortiz Rueda, Gerardo   +1 more
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Instruction Tuning With Loss Over Instructions

Advances in Neural Information Processing Systems 37
NeurIPS 2024.
Zhengyan Shi, Adam X. Yang, Bin Wu 0025, Laurence Aitchison, Emine Yilmaz, Aldo Lipani   +5 more
openaire   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Secourir un train en panne : limites et difficultés à l’écriture des règles de sécurité

Activités, 2012
Risk-prone organisations issue regulations to ensure the stability and safety of the socio-technical system. However, the tendency to over-regulate has its limitations.
Alexandre Largier, Nicolas Lot
doaj   +1 more source

Aktywizowanie rozwoju sprawności słuchania w języku polskim jako ojczystym

Z Teorii i Praktyki Dydaktycznej Języka Polskiego, 2020
The aim of the present article is to present the typology of listening comprehension skills activated during Polish language lessons. What the author claims is that in Polish school two types of listening co-exist, namely: natural and activated.
Marta Urszula Chyb
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source