Results 81 to 90 of about 4,021,411 (294)
The Impact of Instructions on Survey Translation: An Experimental Study
Survey Research Methods, 2009 The experimental study described in this paper examined the impact of providing special instructions and supporting material to translators. Specifically, it addressed whether Spanish, Chinese, and French translators provided with explanatory text and ...
Brian Kleiner, Yuling Pan, Jerelyn Bouic
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Instructions to Authors, Subscribers [PDF]
, 2008 Instructions to authors wishing to contribute and readers wishing to ...
core +4 more sources
EFECTO DEL CONTACTO CON INSTRUCCIONES, LA ESPECIFICIDAD E HISTORIA INSTRUCCIONAL EN LA INSENSIBILIDAD AL CAMBIO CONTINGENCIAL EN TAREAS DE IGUALACIÓN DE LA MUESTRA DE PRIMER ORDEN EN HUMANOS [PDF]
Acta Colombiana de Psicología, 2007 The objective of the present study was to explore if the provision of explicit instructions prior to contingency contact, the degree of instructional specificity, as well as the instructional history of the subjects, affect the sensitivity to the change ...
Bañuelos Pineda, Iris +3 more
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Periodic Single-Pass Instruction Sequences [PDF]
, 2013 A program is a finite piece of data that produces a (possibly infinite) sequence of primitive instructions. From scratch we develop a linear notation for sequential, imperative programs, using a familiar class of primitive instructions and so-called ...
Bergstra, Jan A., Ponse, Alban
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Contextes et Didactiques, 2017 Our study is part of a socio-didactic research that considers the diversity of contexts and of the educational cultures – and by extension of the evaluation cultures – that characterize them. It focuses on taking into account the specificities of foreign
M’hand Ammouden
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