Results 41 to 50 of about 167,121 (266)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Perspectivas académicas sobre la enseñanza virtual en contextos de educación superior

open access: yesEnsayos Pedagógicos
La enseñanza virtual en la educación superior, impulsada por la tecnología y la globalización, ha suscitado interés académico. Este artículo explora perspectivas epistemológicas, ontológicas y axiológicas para comprender la enseñanza virtual.
Chess Emmanuel Briceño Nuñez
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Piloting a Basic Life Support instructor course: A short report. [PDF]

open access: yes, 2022
Aim The aim was to describe a new shortened pilot of the European Resuscitation Council's standard Basic Instructor Course. Methods The four-hour pilot followed a blended learning strategy (pre-course preparation, on-site small-group sessions ...
Nabecker, Sabine   +3 more
core   +2 more sources

Nursing Students\' and Instructors\' Experience about Nursing Fundamental Course: A Qualitative Study [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2009
Introduction: The situations affecting teaching and learning nursing fundamental course may influence acquiring competencies in primary clinical skills. Several reasons have been mentioned for this problem.
Gholamhossein Mahmoudirad   +2 more
doaj  

We Can’t Fail Again: Arguments for Professional Development in the Wake of COVID-19

open access: yesJournal of Microbiology & Biology Education, 2022
The majority of academic institutions were underprepared for a global pandemic, leading to spikes in instructor anxiety and drops in student engagement with STEM courses.
Lisa L. Walsh   +5 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

QUALITY OF SERVICE PROVIDED TO THE CUSTOMER FOR THE GYM INSTRUCTORS

open access: yesRevista Arbitrada Interdisciplinaria Koinonía, 2018
The article aims to determine the quality of the service provided to the athlete by the instructors in gyms in the city of Coro, specifically in the Atlantis Gym.
Dr. Julio Aldana, Lcdo. Jaime Piña
doaj  

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