Results 61 to 70 of about 129,371 (267)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Cross-cultural adaptation of Autism Classification System of Functioning: Social Communication (ACSF: SC) for use in Brazil

Cadernos Brasileiros de Terapia Ocupacional, 2019
Objective: To conduct a cross-cultural adaptation of the instrument: Autism Classification System of functioning: Social communication (ACSF: SC), which allows clinicians to classify the level of the social communication function of children with ...
Débora Santana Eloi, Kesia Kelen Gonçalves Mareco, Adriana Gonçalves Queiroz, Carla Ribeiro Lage, Cecília Pletschette Galvão, Clarice Ribeiro Soares Araújo, Samara de Araújo Costa, Ana Amélia Cardoso   +7 more
doaj   +1 more source

Orientation-Dependent Reflection of Structurally Coloured Butterflies

Biomimetics, 2020
Keywords: orientation-dependent reflection; structural color; butterflies; imprinting technique; instrument ...
Sigrid Zobl, Bodo D. Wilts, Willi Salvenmoser, Peter Pölt, Ille C. Gebeshuber, Thorsten Schwerte   +5 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Translation and cultural adaptation of “Glasgow Children’s Benefit Inventory” into Brazilian Portuguese

Brazilian Journal of Otorhinolaryngology
Objective: Translate and cross-culturally adapt into Brazilian Portuguese the Glasgow Children’s Benefit Inventory instrument used for the quality-of-life assessment after pediatric ENT interventions. Method: This is a methodological study of translation
Caroline Catherine Lacerda Elias, Adriane Ribeiro Teixeira, Maria Eduarda Claro de Souza, Letícia Petersen Schmidt Rosito, Sady Selaimen da Costa   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Just Instruments for Adaptation Finance

Analyse & Kritik, 2018
Abstract The paper discusses Baatz’s work (2018) published in a recent issue of this journal. It first considers the proposed framework of justice within which to evaluate instruments for adaptation finance; it then develops the framework’s criteria of fairness and feasibility further; finally, it proposes an option for increasing the
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Translation and cross-cultural validation of the instrument “Spiritual Assessment Scale” in Brazil

O Mundo da Saúde, 2013
Spirituality is considered an integrant part of nursing care. This study aimed to perform a cross-cultural adaptation of the “Spiritual Assessment Scale” (SAS) to Brazil. A specific instrument for cross-cultural adaptation based on Lynn’s studies (Likert
Elizangela Oliveira Freitas, Margarida Maria da Silva Vieira, Miriam Harumi Tsunemi, Leocir Pessini, Grazia Maria Guerra   +4 more
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